Univasc
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Avoid consuming excessive potassium in foods and supplements (salt substitutes) when taking Univasc. Ask your physician or pharmacist for more information regarding electrolyte balance.1
• Take the medication separated from food by at least 1 hour. Food reduces the absorption of the drug by varying degrees.2
• Avoid alcohol3
• Some herbs possess cardiac activity and they may interact with Univasc to increase side effects: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot4
• Avoid natural licorice products, ginseng, and ephedra (ma huang), which may contribute to high blood pressure.5
• Topical capsaicin may increase the cough associated with the use of ACE inhibitors.6
• These herbs may possess diuretic properties which could result in additive effects with Univasc. They include: Alfalfa, Angelica, Astragalus, Basil, Bean Pod, Buckthorn, Burdock, Butcher’s Broom, Buchu, Celery, Cleavers, Dandelion, Elecampane, Elder, Goat's Rue, Hempnettle, Horsetail, Indian-Hemp, Juniper, Marigold, Meadowsweet, Parsley, Rauwolfia, Sarsaparilla, Sweet clover, Turmeric, and Vervain7
• Avoid yohimbe with Univasc due to possible increased side effects or adverse reactions.8
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Burnakis TG & Mioduch HJ: Combined therapy with captopril and potassium supplementation. A potential for hyperkalemia. Arch Intern Med 1984; 144:2371-2372.
1 Good CB, McDermott L, McCloskey B. Diet and serum potassium in patients on ACE inhibitors. JAMA 1995;274:538.
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
4 Blumenthal M, et al. ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
6 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
6 Hakas JF. Topical capsaicin induces cough in patient receiving ACE inhibitor. Ann Allergy 1990: 65:322
7 Blumenthal M, et al. ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
7 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
7 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
7 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
8 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
8 Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. 1996.
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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