Spectracef
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Consume adequate amounts of fluids, unless otherwise directed.1
• Cephalosporins may cause the improper absorption of some B vitamins and vitamin K.2
• Antibiotics kill bacteria, including beneficial flora in the gut, which could affect digestion and/or elimination. Supplementation with acidophilus or bifidus may aid in restoring this beneficial flora.3
• Avoid antacids with cephalosporins, which may interfere with the medication.4
References1 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
2 Anonymous. New examples of vitamin K-drug interaction. Nutr Rev 1984;42(4):161-63 [review].
2 Hill MJ: Intestinal flora and endogenous vitamin synthesis, Eur J Cancer Prev, 1997, 6 (Suppl 1): S43-5.
2 Deguchi Y, et al: Comparative studies on synthesis of water-soluble vitamins among human species of Bifidobacteria, Argic Biol Chem, 1985, 19 (1): 13-19.
2 Conly J and Stein K: Reduction of vitamin K2 concentrations in human liver associated with the use of broad spectrum antimicrobials, Clin Invest Med, 1994, 17 (6):531-9.
2 Ellenger P, et al: Production and release of nicotinamide by the intestinal flora in man, Nature, 1944, 154:270-271.
3 Bengmark S & Gianotti L: Nutritional support to prevent and treat multiple organ failure. World J Surg, 1996 May, 20:4, 474-81.
3 Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65.
3 Gorbach SL: Bengt E. Gustafsson Memorial Lecture, Function of the Normal Human Microflora, Scand J Infect Dis Suppl, 1986, 49:17-30.
4 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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