Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Possible deficiencies include: Co-Q-10, and Chromium.1
• Calcium supplements may interfere with drug absorption.2
• Use with caution in diabetics, the drug may alter blood sugar levels.3
• Avoid alcohol.4
• Avoid natural licorice products.5
• Meadowsweet, poplar, wintergreen and willow bark all have salicylate properties which may interfere with beta blockers due to the known interaction between salicylates and beta blockers.6
• These herbs may possess cardioactive properties, and should therefore not be taken with antihypertensive drugs: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot.7
• Ephedra, or Ma huang should not be taken together with other CNS stimulants or circulatory agents (digitoxin, beta-blockers, etc.). Theoretically, a single high dose could result in irregular heartbeats.8
• Beta blockers can help prevent Yohimbe toxicity.9
References1 Kishi H, Kishi T, Folkers K: Bioenergetics in clinical medicine III - inhibition of coenzyme Q10-enzymes by clinically used antihypertensive drugs, Res Commun Chem Pathol Pharmacol, 1975, 12(3):533-40.
1 Shand, D.G.: Clinical pharmacology of the beta-blocking drugs: implications for the postinfarction patient. Circulation, 1983, 67(Supp 1): 12-15.
1 Roeback JR Jr, Hla KM, Chambless LE, Fletcher RH. Effects of chromium supplementation on serum high-density lipoprotein cholesterol levels in men taking beta-blockers. A randomized, controlled trial. Ann Intern Med, 1991;115(12):917-924
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999.
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999.
4 Pronsky, Z Food Medication Interactions, 11th edition, 1999.
4 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 Farese, RV et al., Licorice-induced hypermineralcorticoidism. NEJM. 1991, 325:1,1223-1,227
5 Pronsky, Z Food Medication Interactions, 11th edition, 1999.
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
6 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998.
6 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
6 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
7 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
7 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
7 PDR For Herbal Medicines, 2nd edition, Medical Economics Co., 2000.
8 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998.
9 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998.
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.