Pacerone
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Grapefruit juice - People taking this medication should not consume grapefruit juice or eat grapefruit to prvent potentially serious side effects. In one controlled study, drinking grapefruit juice while taking amiodarone dramatically increased blood levels of the drug.1
• Vitamin E - The addition of vitamin E with this medication may help to reduce lung toxicity caused by the medication.2
References1 Libersa CC, Brique SA, Motte KB, et al. Dramatic inhibition of amiodarone metabolism induced by grapefruit juice. Br J Clin Pharmacol 2000;49:373–8.
2 Kachel DL, Moyer TP, Martin WJ 2d. Amiodarone-induced injury of human pulmonary artery endothelial cells: Protection by alpha-tocopherol. J Pharmacol Exp Ther 1990;254:1107–12
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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