Deferoxamine
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• nutrient affecting drug performance: Iron Since deferoxamine is administered to individuals with dangerously high levels of iron it would be counter-productive to supplement with iron. An individual on deferoxamine should consult the prescribing physician before using any supplements containing iron.1
• nutrient affecting drug performance: Vitamin C . Vitamin C supplementation, even at low levels (200 mg per day), has consistently enhanced the ability of deferoxamine to rid the body of excess iron even though vitamin C may slightly increase iron absorption. In twelve studies at different dose levels of deferoxamine, ascorbate therapy was associated with increased iron excretion ranging from 24% to 245%.2
References1 Hoffbrand AV, Wonke B. Iron chelation therapy. J Intern Med Suppl 1997;740:37-41.
1 Hoffbrand AV. Prospects for oral iron chelation therapy. J Lab Clin Med 1994 Apr;123(4):492-494.
1 Hoffbrand AV. Prospects for oral iron chelation therapy. J Lab Clin Med 1994 Apr;123(4):492-494.
1 Sakagami H, Satoh K, Fukuchi K, Gomi K, Takeda M. Effect on an iron-chelator on ascorbate-induced cytotoxicity. Free Radic Biol Med 1997;23(2):260-270
2 (Hussain MA, et al. Lancet 1977 May 7;1(8019):977-979.)
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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