Tamoxifen
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Tamoxifen may cause deficiencies in beta-carotene. Discuss supplementation with your physician or pharmacist.1
• This drug may cause serum calcium levels to increase, and it is important to discuss calcium intake with your physician before using calcium supplements. Separate calcium and magnesium supplements from the medication by at least 2 hours.2
• A study has shown melatonin to be helpful when used together with Tamoxifen in the treatment of metastatic breast cancer.3
• The following herbs may exhibit hormonal properties, this may inhibit the action of Tamoxifen: Black Cohosh, Bugleweed, Chaste Tree, Dong Quai, and False Unicorn Root.4
References1 Potischman N et al., Effects of breast cancer treatments on plasma nutrient levels: implications for epidemiological studies. Cancer Epidemiol Biomarkers Prev, 1992 Nov-Dec, 1:7, 555-9.
2 Drug Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Lissoni P, Barni S, Meregalli S, et al. Modulation of cancer endocrine therapy by melatonin: A phase II study of tamoxifen plus melatonin in metastatic breast cancer patients progression under tamoxifen alone. Br J Cancer 1995;71:854-56.
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996:21,45,63,282.
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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