Temazepam
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Alcohol can increase both the sedative and the intoxifying effects of Temazepam. Alcohol use should be avoided.1
• Avoid caffeine found in sodas, coffee, teas or chocolate. Nutritional supplements containing caffeine should also be avoided.2
• Grapefruit juice may interact with some benzodiazepines by increasing their duration of effect, the clinical significance of this is unknown.3
• Tobacco may reduce the effects of Temazepam by speeding its elimination from the body.4
• The following herbs have sedative qualities and could intensify the effects of Temazepam: calamus, calendula, chamomile, California poppy, catnip, couch grass, elecampane, ginseng Siberian, goldenseal, gotu kola, hops, Jamaican dogwood, kava, lemon balm, sage, St. John's wort, sassafras, scullcap, shepherd's purse, stinging nettle, valerian, withania root, and yerba mansa.5
• The combination of Kava kava and Temazepam may have additive sedating effects. Kava kava should not be used while taking this medication.6
• Avoid cola, cocoa, green tea, guarana and mate with temazepam due to their caffeine content.7
References1 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999.
1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Rybacki, JJ. Concise Essential Guide to Prescription Drugs. HarperCollins, 1997.
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Ozdemir M, Aktan Y, Boydag BS. Interaction between grapefruit juice and diazepam in humans. Eur J Drug Metab Pharmacokinet 1998; 23:55-9
4 Ferguson, T: The Smoker’s Book of Health, New York, 1987.
4 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
5 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
6 Davies LP, Drew CA, Duffield P, et al. Kava pyrones and resin: Studies on GABAA, GABAB and benzodiazepine binding sites in rodent brain. Pharm Toxicol 1992;71:120-26.
6 Holm E, Staedt U, Heep J, et al. Studies on the profile of the neurophysiological effects of D,L-kavain: Cerebral sites of action and sleep-wakefulness rhythm in animals. Arzneim Forsch 1991;41:673-83.
6 Almeida JC. Coma from the health food store: Interaction between kava and alprazolam. Ann Intern Med 1996;125:940-41.
7 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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