Humulin R
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Follow a diabetic meal plan with direction from your physician and pharmacist.1
• The use of alcohol should be limited, as it can interfere with diabetes management.2
• Potatoes can interfere with blood sugar levels and insulin dosage may require adjustment.3
• Avoid magnesium and vitamin E supplements together with insulin due to possible increased effects.4
• Psyllium seeds fiber may affect dosing levels when used with insulin. Discuss fiber supplementation with your pharmacist or physician. Always take fiber supplements apart from medication and other nutritional supplements.5
• The following herbs may affect blood sugar levels: Alfalfa, Aloe vera, Burdock, Celery, Cornsilk, Damiana, Eucalyptus, Garlic, Ginger, Ginseng, Juniper, Marshmallow, Myrrh, Nettle, Sage and Tansy.6
• Fenugreek has been shown to lower blood glucose levels, and should be used with caution in combination with Humulin.7
References1 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
2 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Gannon MC, et al. Diabetes Care 1993;16:874.
3 The Review of Natural Products, Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Ceriello A, Giugliano D, Quatraro A, Donzella C, Dipalo G, Lefebvre PJ. Vitamin E reduction of protein glycosylation in diabetes. New prospect for prevention of diabetic complications? Diabetes Care. 1991 Jan;14(1):68-72.
4 McBain AM, Brown IR, Menzies DG, Campbell IW. Effects of improved glycaemic control on calcium and magnesium homeostasis in type II diabetes. J Clin Pathol 1988;41:933-35.
4 Paolisso G, D'Amore A, Giugliano D, et al. Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin-dependent diabetic patients. Am J Clin Nutr 57:650-656, 1993.
5 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998.
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
6 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996:21,45,63,282.
6 Facts and Comparisons, The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
6 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
6 Neef H, et al. Inhibitory effects of Galega officinalis on glucose transport across monolayers of human intestinal epithelial cells (Caco-2). Pharm Pharmacol Lett 1996;6(2):86-89.
7 Sharma RD, Raghuram TC, Sudhakar Rao N. Effect of fenugreek seeds on blood glucose and serum lipids in type 1 diabetes. Eur J Clin Nutr 1990;44:301-6.
7 Sharma RD, Sakar A, Hazra DK, et al. Use of fenugreek seed powder in the management of non-insulin dependent diabetes mellitus. Nutr Res 1996;16:1131-39.
7 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996:21,45,63,282.
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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