Baycol
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Avoid or limit alcohol1
• Avoid grapefruit juice with this medication, it may theoretically interact with the drug.2
• Baycol may deplete Co-Q-10 levels. There are several studies that show the HMG-CoA Reductase Inhibitors inhibit the biosynthesis of Co-Q-10.3
• Red yeast rice contains ingredients similar to the statin drugs and may have additive effects if used together.4
• These herbs have approval status by the German Commission E regarding this specific action (cholesterol lowering): Psyllium seed, blonde Psyllium seed husk.5
• These herbs have shown hypocholesterolic effects: Artichoke Plant, Fenugreek, Garlic Plant, Plantain. They may have additive effects with Baycol, consult a pharmacist regarding their use together.6
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Lilja JJ, Kivisto KT, Neuvonen PJ. Grapefruit juice increases serum concentrations of atorvastatin and has no effect on pravastatin. Clin Pharmacol Ther 1999; 66:118-27.
3 Bargossi AM, Battino M, Gaddi A, et al. Exogenous CoQ10 preserves plasma ubiquinone levels in patients treated with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Int J Clin Lab Res 24: 171-176, 1994.
3 Folkers K, et al. Lovastatin decreases coenzyme Q levels in humans. Proc Natl Acad Sci USA 87(22): 8931-8934, 1990.
3 Ghirlanda G, et al. Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study. J Clin Pharmacol 33(3): 226-229, 1993.
3 Mortensen SA, et al. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Mol Aspects Med 18(Suppl.): S137-S144, 1997.
4 McKevoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998
4 The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 2000
5 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998.
6 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
6 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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