Clonidine
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Maintain a low calorie, low-fat diet with high fiber intake as directed by your physician.1
• Limit alcohol use.2
• Clonidine may contribute to the depletion of CoQ10. Supplementation may be beneficial.3
• Some herbs possess cardiac properties that may intensify the action of antihypertensive drugs. This could result in an excessive lowering of blood pressure or increased side effects. Such herbs include: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot4
• Avoid natural licorice products, Ginseng, and Ephedra (Ma huang) which may interfere with antihypertensive therapy.5
• Avoid Yohimbe, which may reverse the effects of Clonidine.6
References1 Balch, JF, Balch PA: Prescription for Nutritional Healing, Avery Publishing, 1997
2 Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 143.
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Kishi H, Kishi T, Folkers K: Bioenergetics in clinical medicine III - inhibition of coenzyme Q10-enzymes by clinically used antihypertensive drugs, Res Commun Chem Pharmacol, 1975, 12(3):533-40.
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
4 McGuffin M, et al., ed. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997.
4 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
5 Farese, RV et al., Licorice-induced hypermineralcorticoidism. NEJM. 1991, 325:1,1223-1,227.
5 Pronsky, Z Food Medication Interactions, 11th edition, 1999
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
6 DeSmet PAGM, Smeets OSNM. "Potential risks of health food products containing yohimbe extracts," Br. Med. J., 309:958, 1994.
6 Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
6 Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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