Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Makers of this medication suggest that any multivitamins should be taken apart from this medication by at least several hours.1
• Foods high in fat can delay peak concentration of the drug, but overall absorption is increased.2
• Sodium and Potassium - Controlled studies indicate that individuals on low-salt diets who take this type of medication retain sodium and potassium, which might result in higher than normal blood levels of these minerals. These minerals in foods and supplements may cause problems when taken with this medication. Until more information is available, people taking this medication should have their sodium and potassium blood levels monitored by their healthcare practitioner.3
• The drug can cause gastrointestinal pain and diarrhea. If this persists talk to a doctor or pharmacist.4
• Drink plenty of fluids while on this medication and do not use the drug if dehydration is present.5
• Avoid herbs with antiplatelet or anticoagulant properties like: angelica,anise, asafoetida, capsicum, celery, chamomile, clove, danshen, fenugreek, feverfew, garlic, ginger, ginkgo, ginseng (Panax), horse chestnut, horseradish, licorice, meadowsweet, prickly ash, onion, passionflower, poplar, red clover, turmeric, wild carrot, wild lettuce, and willow with this medication. Avoid their use together.6
References1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Rossat J, Maillard M, Nussberger J. Renal effects of selective cyclooxygenase-2 inhibition in normotensive salt-depleted subjects. Clin Pharmacol Ther 1999;66:76–84.
4 Pronsky, Z Food Medication Interactions, 11th edition, 1999
5 Pronsky, Z Food Medication Interactions, 11th edition, 1999
6 Pronsky, Z Food Medication Interactions, 11th edition, 1999
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.