Triamterene w/ HCTZ
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Triamterene may contribute to the depletion of folic acid in people predisposed to folic acid deficiency. Supplementation may be useful for these individuals. Discuss the need for supplementation with a pharmacist or physician.1
• Do not supplement with potassium unless prescribed by a physician. Even though triamterene is a diuretic, it does not deplete potassium stores.2
• Supplementation with calcium, and magnesium may be beneficial. Consult a pharmacist or physician prior to initiating therapy.3
• Avoid natural licorice products. Licorice may cause excessive potassium loss with long term use.4
• Avoid these herbs with diuretic action: Alfalfa, Angelica, Astragalus, Basil, Bean Pod, Buckthorn, Burdock, Butcher’s Broom, Buchu, Celery, Cleavers, Cornflower, Dandelion, Elecampane, Elder, Goat's Rue, Hempnettle, Horsetail, Indian-Hemp, Juniper, Marigold, Meadowsweet, Parsley, Rauwolfia, Sarsaparilla, Sweet clover, Turmeric, and Vervain5
References1 Jackson EK. Diuretics. In Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 9th ed. New York: McGraw Hill, 1996, 706.
1 Lambie DG, Johnson RH: Drugs and folate metabolism, Drugs, 1985, 30(2):145-55.
1 Joosten E, Pelemans W: Megaloblastic anaemia in an elderly treated with triamterene, Neth J Med, 1991, 38(5-6):209-11.
1 Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, p 268.
2 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
2 Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, p. 269.
3 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
3 Werbach WR. Foundations of Nutritional Medicine. Tarzana, CA: Third Line Press, 1997, 246 [review].
3 Hanze S, Seyberth H: Studies of the effect of diuretics furosemide, ethacrynic acid, and triamterene on renal magnesium and calcium excretion, Klin Wochenschr, 1967, 45(6):313-4.
3 D’Arcy PF, Griffin JP: latrogenic diseases, New York, NY: Oxford University Press, 1972.
4 Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999.
4 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 Facts and Comparisons, Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
5 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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