Methyldopa
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• There may be an increased requirement for vitamins B12 and folic acid with high doses of the drug.1
• Avoid taking iron supplements with methyldopa, iron decreases absorption of the drug.2
• Avoid alcohol.3
• Co-Q-10 may become deficient with long term methyldopa use.4
• Avoid natural licorice with methyldopa, because it may cause hypertension.5
References1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
1 Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 74.
2 McKevoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Campbell NR and Hasinoff BB. Iron supplements: A common cause of drug interactions. Br J Clin Pharmacol 31: 251-255, 1991.
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 Kishi H, et al. Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q10-enzymes by clinically used anti-hypertensive drugs. Res Commun Chem Pathol Pharmacol 12(3): 533-540, 1975
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
5 Pronsky, Z Food Medication Interactions, 11th edition, 1999
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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