Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Food can reduce the absorption of the drug. Take the suspension form 1 hour after or 2 hours before a meal.1
• Vitamin K levels may decrease with prolonged cephalosporin use. Monitor prothrombin levels while on these antibiotics.2
• Antibiotics kill bacteria, including beneficial flora in the gut, which may affect digestion and/or elimination. Supplementation with acidophilus and/or bifidus may help to replace this beneficial flora.3
• Avoid alcohol.4
• Levels of B vitamins may be reduced with long term cephalosporin use. Consult a pharmacist regarding need for supplementation.5
• Feverfew, Ginkgo and Garlic all have anticoagulant properties, this may theoretically interfere with some cephalosporins, due to their known interactions with coumadin.6
References1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Shils M, et al. (eds.). Modern nutrition in health and disease, 9th ed. Baltimore: Williams and Wilkins, 1999: 1634
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Bengmark S & Gianotti L: Nutritional support to prevent and treat multiple organ failure. World J Surg, 1996 May, 20:4, 474-81.
3 Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65.
3 Gorbach SL: Bengt E. Gustafsson Memorial Lecture, Function of the Normal Human Microflora, Scand J Infect Dis Suppl, 1986, 49:17-30.
4 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65
5 Hill MJ: Intestinal flora and endogenous vitamin synthesis, Eur J Cancer Prev, 1997, 6 (Suppl 1): S43-5.
6 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
6 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.