Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Take with food to reduce stomach upset and increase drug absorption1
• Take antacids or certain supplements (magnesium) separated by at least 2 hours from the drug.2
• May cause appetite changes, nausea/vomiting3
• The following herbs: Angelica, anise, arnica, asafoetida, bogbean, boldo, fenugreek, feverfew, garlic, ginger, ginkgo, ginseng (Panax), horse chestnut, licorice, meadowsweet, prickly ash, passionflower, poplar, quassia, red clover, turmeric, and willow, may potentiate the effects of platelet aggregation inhibitor drugs such as ticlid.4
• Due to presence of salicylates in, meadowsweet, European poplar, queen of the meadow or willow, they may potentiate the effects of Ticlid.5
• The German Commission E has also noted the possible anticoagulant effect of bromelain and Cinchona bark.6
• The chinese herb Dan shen has anticoagulant properties which may interact with Ticlid.7
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
4 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
4 Rosenblatt M, Mindel J. Spontaneous hyphema associated with ingestion of Ginkgo biloba extract. New Engl J Med 1997;336:1108
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
4 Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Safety 1997;17(5):342-56
4 Rose KD et al., Spontaneous spinal epidural hematoma with associated platelet dysfunction from excessive garlic ingestion. A case report. Neurosurgery 1990;26(5):880-2
5 Newall CA, Anderson LA, Phillipson JD. »Herbal« Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
6 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
7 Yu CM, Chan JCN, Sanderson JE. Chinese herbs and warfarin potentiation by danshen. J Intern Med 1997;241:337-39.
7 Tam LS, Chan TYK, Leung WK, Critchley JAJH. Warfarin interactions with Chinese traditional medicines: Danshen and methyl salicylate medicated oil. Aust NZ J Med 1995;25:258.
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.