Starlix
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Strenuous physical exercise, drinking alcoholic beverages, or not eating enough can increase risk of your blood sugar becoming too low when taking Starlix.1
• Diabetes may be affected by many nutritional deficiencies, and using diabetic medications may increase the body’s nutritional needs. Ask your physician about supplementing the diet with a multivitamin.2
• High doses of the vitamin niacin may increase blood glucose levels. Excessive use of this nutrient should be avoided.3
• Alcohol use should be limited since it can interfere with diabetes management.4
• It may be advisable to avoid glucosamine in diabetes. It may raise insulin resistance.5
• The following herbs may lower blood sugar levels: Alfalfa, Aloe vera, Bilberry leaf, Burdock, Bitter Melon, Celery, Cornsilk, Damiana, Eucalyptus, Fenugreek, Garlic, Ginger, Panax Ginseng, Goat's Rue, Juniper, Marshmallow, Myrrh, Nettle, Onions, Sage and Tansy.6
References1 FDA Consumer Information, December 2000.
2 "The Medical Letter on Drugs and Therapeutics," (New Rochelle, NY, The Medical Letter, Inc.) thru Vol. 37 (952), July, 1995.
2 Berger W, Incidence of severe side effects during therapy with sulfonylureas and biguanides, Horm Metab Res Suppl, 1985, 15:111-5.
2 Rieder HP, Berger W, and Fridrich R: Vitamin status in diabetic neuropathy, Z Ernahrungswiss, 1980, 19 (1):1-13.
2 Carpentier JL, Bury J, Luyckx A, et al: Vitamin B12 and folic acid serum levels in diabetics under various therapeutic regimens, Diabete Metab, 1976, 2(4):187-90.
3 Balch JF, Balch PA: Prescription for Nutritional Healing, 1997, p. 231.
3 Schwartz ML. Severe reversible hyperglycemia as a consequence of niacin therapy. Arch Intern Med. 1993 Sep 13;153(17):2050-2.
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 Graedon J, Graedon T: The People’s Guide to Deadly Drug Interactions, 1995, p. 284.
4 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Pronsky, Z Food Medication Interactions, 11th edition, 1999
5 Miles PD, Higo K, Olefsky JM. Exercise-stimulated glucose turnover in the rat is impaired by glucosamine infusion. Diabetes. 2001 Jan;50(1):139-42.
5 Ross SA, Chen X, Hope HR, Sun S, McMahon EG, Broschat K, Gulve EA. Development and comparison of two 3T3-L1 adipocyte models of insulin resistance: increased glucose flux vs glucosamine treatment. Biochem Biophys Res Commun. 2000 Jul 14;273(3):1033-41.
5 Monauni T, Zenti MG, Cretti A, Daniels MC, Targher G, Caruso B, Caputo M, McClain D, Del Prato S, Giaccari A, Muggeo M, Bonora E, Bonadonna RC. Effects of glucosamine infusion on insulin secretion and insulin action in humans. Diabetes. 2000 Jun;49(6):926-35.
5 The Review of Natural Products, Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
6 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
6 Bever BO and Zahnd GR. Plants with oral hypoglycemic action. Q J Crude Drug Res 17: 139-196, 1979.
6 Welihinda J, et al. Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes. J Ethnopharmacol 17: 277-282, 1986.
6 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
6 Yongchaiyudha S, Rungpitarangsi V, Bunyapraphatsara N, et al. Antidiabetic activity of Aloe vera L. juice. I. Clinical trial in new cases of diabetes mellitus. Phytomedicine. 1996;3:241-243.
6 Neef H, et al. Inhibitory effects of Galega officinalis on glucose transport across monolayers of human intestinal epithelial cells (Caco-2). Pharm Pharmacol Lett 1996;6(2):86-89.
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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