Amiodarone HCl
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Monitor magnesium and potassium levels while on this medication.1
• Vitamin E may prevent pulmonary artery damage caused by amiodarone.2
• Avoid Ma huang with amiodarone because the herb could cause irregular heartbeats.3
• Night-blooming Cereus has approval status by the German Commission E regarding its ability to stabilize arrhythmia, however the herb should not be used together with an antiarrhythmic drug without consulting a pharmacist or physician due to possible additive effects.4
• The German Commission E also notes the possibility for chronic use of rhubarb, or senna to deplete potassium resources thereby potentiating the effects of antiarrhythmic drugs.5
• It may be advisable to avoid these herbs with cardiac activity: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot6
References1 Pronsky, Z Food Medication Interactions, 11th edition, 1999.
1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Kachel DL et al. Amiodarone-induced injury of human pulmonary artery endothelial cells: Protection by alpha-tocopherol. J Pharmacol Exp Ther 1990;254:1107-12.
2 Honegger UE, Scuntaro I, Wiesmann UN. Vitamin E reduces accumulation of amiodarone and desethylamiodarone and inhibits phospholipidosis in cultured human cells. Biochem Pharmacol. 1995 Jun 16;49(12):1741-5.
3 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998.
4 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
5 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
6 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
6 The Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000
6 Blumenthal M, et al. ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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