Data provided by Applied Health
side effects, nutrient depletions, herbal interactions and health notes:
• Take with food or milk for stomach upset.1
• Avoid alcohol2
• Avoid taking cefaclor together with antacids, because they could interfere with drug absorption.3
• Antibiotics may kill friendly intestinal bacteria. They may also cause an overgrowth of other bacteria or fungus (candidiasis). Supplementation with acidophilus or bifidus (probiotics) may alleviate superinfections or oral thrush4
• The B vitamins may be depleted with longterm antibiotic use. Supplementation may be necessary.5
• Sodium content may be an issue for those on a low sodium diet6
• Cephalosporins may affect vitamin K levels in the body. Although short term use of these antibiotics are not associated with any problems, longer durations of use may pose risks.7
• Feverfew, Ginkgo and Garlic all have anticoagulant properties, this may theoretically interfere with some cephalosporins, due to their known interactions with coumadin.8
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000.
4 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65
4 Bengmark S & Gianotti L: Nutritional support to prevent and treat multiple organ failure. World J Surg, 1996 May, 20:4, 474-81.
4 Gorbach SL: Bengt E. Gustafsson Memorial Lecture, Function of the Normal Human Microflora, Scand J Infect Dis Suppl, 1986, 49:17-30
5 Cummings JH, Macfarlane G: Role of intestinal bacteria in nutrient metabolism, JPEN J Parenter Enteral Nutr, 1997, 21(6): 357-65
5 Deguchi Y, et al: Comparitive studies on synthesis of water-soluble vitamins among human species of Bifidobacteria, Argic Biol Chem, 1985, 19 (1): 13-19.
6 Pronsky, Z Food Medication Interactions, 11th edition, 1999
7 Anonymous. New examples of vitamin K-drug interaction. Nutr Rev 1984;42(4):161-63 .
7 Shils M, et al. (eds.). Modern nutrition in health and disease, 9th ed. Baltimore: Williams and Wilkins, 1999: 1634
8 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
8 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.