Prilosec
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• This medication may affect the proper absorption of beta carotene, iron and vitamin B12. Consult your pharmacist regarding supplementation.1
• Avoid alcohol with this drug.2
• Prilosec may interact with St. John's Wort to increase the risk of photosensitivity.3
• Acacia, Black mustard, Capsicum, Devil's Claw, Goldenseal,and Horseradish, all increase gastric acid and could therefore theoretically interact with Prilosec.4
References1 Drug Interaction Facts, Tatro, D.S., Editor (St. Louis, MO, Facts and Comparisons, through July 1995)
1 Bradford GS, Taylor CT: Omeprazole and vitamin B12 deficiency, Ann Pharmacother 1999 May;33(5):641-3.
1 Termanini B, Gibril F, Sutliff VE, et al. Effect of long-term gastric acid suppressive therapy on serum vitamin B12 levels in patients with Zollinger-Ellison syndrome. Am J Med 1998;104:422-30.
1 Koop H, Bachem MG. Serum iron, ferritin, and vitamin B12 during prolonged omeprazole therapy. J Clin Gastroenterol 1992;14:288-92.
1 Bellou A, Aimone-Gastin I, De Korwin JD, et al: Colbalamin deficiency with megaloblastic anemia in one patients under long-term omeprazole therapy, J Intern Med, 1996, 240(3): 161-4.
1 Saltzman JR, Kemp JA, Golner BB, et al: Effect of hypochlorhydria due to omeprazole treatment or atrophic gastritis on protein-bound vitamin B12 absorption, J Am Coll Nutr, 1994, 13 (6):584-91.
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
1 Tang G, Serfaty-Lacronsniere C, Camilo ME, Russell RM. Gastric acidity influences the blood response to a beta-carotene dose in humans. Am J Clin Nutr 1996;64:622-26.
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Mirossay A, Mirossay L, Tothova, et al. Potentiation o fhypericin an dhypocrellin-induced phototoxicity by omeprazole. Phytomedicine 6(5): 311 - 317, 1999.
3 Seigers Cp, et al. Phototoxicity caused by hypericum. Nervehielkunde 12: 320 - 322, 1993.
4 PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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