Nardil
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Nardil may cause Tyramine reactions: (i.e. hypertension) if high-tyramine foods (e.g. Aged cheese or wine, bean curd, protein extracts, etc.) are consumed.1
• Avoid caffeine because it could initiate hypertensive crisis.2
• Certain foods should be used with caution: chocolate, avocadoes, raspberries, dairy products. For a complete list of foods to avoid consult a pharmacist.3
• Avoid alcohol.4
• Oils of dill, fennel, parsley and other tyrosine containing foods should be avoided with MAOI’s.5
• California poppy, Nutmeg, Yohimbe and Ginkgo may potentiate the effects of the MAO inhibitors.6
• Cocoa, coffee, cola, guarana, mate, tea can all cause hypertensive crisis together with MAOI’s.7
• Indian Snakeroot can increase the potential for a hypertensive crisis.8
• Concurrent use of ginseng with phenelzine has resulted in manic-like symptoms.9
• Ma huang can induce toxicity with MAOI's and should be avoided for 2 weeks after stopping MAOI's.10
• Nutmeg and St. John's Wort inhibit MAOI's which may potentiate the action of psychoactive drugs.11
References1 Brown CS & Bryant SG, Monoamine oxidase inhibitors: safety and-efficacy issues, Drug Intell Clin Pharm 1988; 22:232-235.
1 McCabe BJ. Dietary tyramine and other pressor amines in MAOI-regimens: a review. J Am Diet Assoc 1986; 86:1059-1064.
1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Pronsky, Z Food Medication Interactions, 11th editon, 1999.
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 McCabe BJ. Dietary tyramine and other pressor amines in MAOI-regimens: a review. J Am Diet Assoc 1986; 86:1059-1064
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Pronsky, Z Food Medication Interactions, 11th edition, 1999.
4 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
5 McCabe BJ. Dietary tyramine and other pressor amines in MAOI-regimens: a review. J Am Diet Assoc 1986; 86:1059-1064.
5 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
6 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Pulbications, 1998.
7 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998.
8 McKevoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
9 Jones BD, Runikis AM. "Interaction of ginseng with phenelzine." J Clin Psychopharmcol, 1987;7:201-202
9 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998.
10 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998.
11 McGuffin M, et al., ed. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997
11 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998.
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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