Parnate
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Avoid foods high in tyramine content: most types of cheese, luncheon meats, yogurt, raspberries, bananas, bean curd, soy sauce and others. Speak to a pharmacist for the full list of foods to avoid.1
• Avoid tryptophan2
• Avoid alcohol3
• Limit or avoid caffeine with Parnate to prevent blood pressure increases.4
• Oils of dill, fennel, parsley and other tyrosine containing foods should be avoided with MAOI’s.5
• California poppy, Nutmeg, Yohimbe and Ginkgo may potentiate the effects of the MAO inhibitors.6
• Cocoa, coffee, cola, guarana, mate, tea can all cause hypertensive crisis together with MAOI’s.7
• Indian Snakeroot can increase the potential for a hypertensive crisis.8
• Licorice, and passion flower can increase side effects of MAOI’s9
• SAMe might protect the liver against MAOI damage.10
• Alfalfa, Anise, Calamus, Capsicum, Cereus, Fenugreek, Yohimbe, all interact with MAOI.11
• Ma huang can induce toxicity with MAOI's and should be avoided for 2 weeks after ceasing MAOI's.12
• Nutmeg and St. John's Wort inhibit MAOI's .13
• The German Commission E has noted an interaction between MAO inhibitors and these herbs: Ephedra and Brewer's yeast.14
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
1 Pronsky, Z Food Medication Interactions, 11th edition, 1999
2 Pronsky, Z Food Medication Interactions, 11th edtion, 1999
2 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 Pronsky, Z Food Medication Interactions, 11th edition, 1999
5 McCabe BJ. Dietary tyramine and other pressor amines in MAOI-regimens: a review. J Am Diet Assoc 1986; 86:1059-1064.
6 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
7 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
8 McKevoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998
9 Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996
9 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
10 Friedel HA, Goa KL, Benfield P. "S-adenosyl-L-methionine. A review of its pharmacological properties and therapeutic potential in liver dysfunction and affective disorders in relation to its physiological role in cell metabolism." Drugs, 1989; 38(3):389-416.
11 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998.
11 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
12 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
13 McGuffin M, et al., ed. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997
13 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
14 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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