Tetracycline
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Take medication one hour before or two hours after food or milk1
• Drink plenty of fluids unless otherwise directed2
• Take calcium, iron, magnesium, zinc or other multivitamins or antacids separated by at least three hours from tetracycline.3
• B vitamins, vitamin K, folic acid and potassium can be depleted with long term use of tetracycline.4
• Diary products can interfere with tetracyclines. Avoid their use within 2 hours of the medication.5
• Bromelain increases antibiotic effects, consult a physician or pharmacist before using both products together.6
• Alfalfa is high in iron, this may cause it to interfere with the absorption of tetracyclines. This is especially true if large quantities of the herb are ingested within two hours of taking tetracyclines7
• The compound berberine found in barberry and goldenseal may decrease the absorption of tetracycline.8
References1 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
2 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Pronsky, Z Food Medication Interactions, 11th edition, 1999
3 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
4 Pronsky, Z Food Medication Interactions, 11th edition, 1999
4 Holt GA. Food & Drug Interactions. Chicago: Precept Press, 1998, 256-58.
5 McKevoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 2000
5 Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
6 Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
6 Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
7 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
7 Neuvonen, P.J., et.al. 1970. Interference of iron with the absorbtion of tetracyclines in man. British Medical J, 4: 532.
8 Khin-Maung-U, Myo-Khin, Nyunt-Nyunt-Wai, et al. Clinical trial of berberine in acute watery diarrhoea. Br Med J 1985;291:1601-05.
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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