Accolate
side effects, nutrient depletions, herbal interactions and health notes:
Data provided by Applied Health
• Do not take this medication and fiber supplements at the same time. Separate their use by at least two hours.1
• Food has been shown to reduce the absorption of Accolate. Take Accolate two to four hours before or after a meal.2
• Accolate may interact with a Japanese herbal formula, Saiboku-to. This formula contains the herbs Ogon, Koboku, and Kanzo.3
References1 Adkins JC & Brogden RN: Zafirlukast. A review of its pharmacology and therapeutic potential in the management of asthma. Drugs, 1998 Jan, 55:1, 121-44.
1 Suissa S et al., Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma. A randomized, double-blind, placebo-controlled trial. Ann Intern Med, 1997 Feb, 126:3, 177-83.
2 Adkins JC & Brogden RN: Zafirlukast. A review of its pharmacology and therapeutic potential in the management of asthma. Drugs, 1998 Jan, 55:1, 121-44.
2 Suissa S et al., Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma. A randomized, double-blind, placebo-controlled trial. Ann Intern Med, 1997 Feb, 126:3, 177-83.
3 Kobayashi I et al., Saiboku-To, a herbal extract mixture, selectively inhibits 5-lipoxygenase activity in leukotriene synthesis in rat basophilic leukemia-1 cells. J Ethnopharmacol, 1995 Aug, 48:1, 33-41.
3 Kobayashi I et al., [Inhibitory effects of saiboku-to and compornent herbs on the production of peptide leukotrienes (LTs) and LTB4]. Arerugi, 1996 Jun, 45:6, 577-83.
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Disclaimers
The information in Drug Watch is provided as a courtesy to NewsTarget readers by Applied Health Solutions in cooperation with Healthway Solutions. Although the information is presented with scientific references, we do not wish to imply that this represents a comprehensive list of considerations about any specific drug, herb or nutrient. Nor should this information be considered a substitute for the advice of your doctor, pharmacist, or other healthcare practitioner. Please read the disclaimer about the intentions and limitations of the information provided on these pages. It is important to tell your doctor and pharmacist about all other drugs and nutritional supplements that you are taking if they are recommending a new medication. Copyright © 2007 by Applied Health Solutions, Inc. All rights reserved.
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