Benefits of flavanol supplementation in treating obesity
07/23/2020 // Evangelyn Rodriguez // Views

Researchers at the Virginia Polytechnic Institute and State University and Ohio State University evaluated the preventive effects of grape seed and pine bark flavanol supplementation in the context of a high-fat diet (HFD). Their findings were published in the journal Nutrition Research.

  • Weight gain and obesity are associated with increased levels of pro-inflammatory cytokines.
  • According to studies, dietary flavanols can reduce the severity of metabolic aberrations caused by an HFD.
  • The degree of polymerization of flavanols also appears to play a role in determining the extent of their protective effects.
  • The researchers fed mice 35 mg/kg body weight grape seed or pine bark daily for 13 weeks as part of an HFD then compared them with mice fed a low-fat diet and mice fed an HFD without flavanol supplementation (control).
  • The group that received grape seed, which gained the most weight overall, had the lowest levels of interleukin-6.
  • Low-dose flavanol supplementation, regardless of the mean degree of polymerization, reduced cytokine production despite increasing weight gain.

Based on these findings, the researchers concluded that flavanols have obesity-independent effects that may be useful for ameliorating inflammation linked to obesity and diabetes. They also believe that flavanol-induced hyperphagia may help attenuate cachexia.

Journal Reference:

Griffin LE, Fausnacht DW, Tuzo JL, Addington AK, Racine KC, Zhang H, Hughes MD, England KM, Bruno RS, O'keefe SF, et al. FLAVANOL SUPPLEMENTATION PROTECTS AGAINST OBESITY-ASSOCIATED INCREASES IN SYSTEMIC INTERLEUKIN-6 LEVELS WITHOUT INHIBITING BODY MASS GAIN IN MICE FED A HIGH-FAT DIET. Nutrition Research. June 2019;66:32–47. DOI: 10.1016/j.nutres.2019.03.011



Take Action:
Support Natural News by linking to this article from your website.
Permalink to this article:
Copy
Embed article link:
Copy
Reprinting this article:
Non-commercial use is permitted with credit to NaturalNews.com (including a clickable link).
Please contact us for more information.
Free Email Alerts
Get independent news alerts on natural cures, food lab tests, cannabis medicine, science, robotics, drones, privacy and more.
App Store
Android App
eTrust Pro Certified

This site is part of the Natural News Network © 2022 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

This site uses cookies
Natural News uses cookies to improve your experience on our site. By using this site, you agree to our privacy policy.
Learn More
Close
Get 100% real, uncensored news delivered straight to your inbox
You can unsubscribe at any time. Your email privacy is completely protected.