Based on these findings, the researchers concluded that carnosine inhibits the migration and intravasation of human CRC cells by suppressing NF-kB activity and modulating MMP and EMT-related gene expression.
Hsieh SL, Hsieh S, Lai PY, Wang JJ, Li CC, Wu CC. CARNOSINE SUPPRESSES HUMAN COLORECTAL CELL MIGRATION AND INTRAVASATION BY REGULATING EMT AND MMP EXPRESSION. The American Journal of Chinese Medicine. 2019;47(02):477–494. DOI: 10.1142/s0192415x19500241