The team used a two-pronged approach in their experiments. First, they used a chronic restraint stress mouse model to determine the plant's antidepressant and antioxidant effects. To determine the efficacy of sea bilberry treatment, they measured biomarkers for stress and depression after restraining the rodents. Second, they used a hydrogen peroxide-induced neuronal damage model to understand the bioactive components behind the plant's antioxidant properties.
The researchers observed that mice treated with sea bilberry exhibited reduced stress and depression-related biomarkers in their brain after being subjected to chronic restraint stress. In addition, sea bilberry protected neuronal cells from damage after being exposed to hydrogen peroxide.
The researchers concluded that sea bilberry possesses potent antioxidant and antidepressant properties.
It is estimated that over 19 million Americans suffer from depression every year. This makes it one of the most common disorders both in the U.S. and around the world. Conventional treatments for depression include drug therapies, which don't work for everyone and can even cause severe side effects, such as insomnia, agitation, weight gain, memory loss, and loss of libido.
Worse still, using antidepressants can also increase the risk of suicidal thoughts, especially in children, teens, and young adults. These are also known to be highly addictive and don't play well with other drug treatments.
For those looking for drug-free alternatives for treating depression, here are some natural antidepressant supplements that offer relief without the nasty side effects. (h/t to BeBrainFit.com)
A popular yet controversial herb for treating depression is St. John's wort. While it's known to be a potent alternative to most antidepressants, it can also increase the risk of side effects similar to commercial drugs. People looking to try the herb must first consult with a healthcare professional, since it's known to react negatively to a lot of pharmacological substances, both synthetic and natural.
BeatDepression.news has the latest on natural treatments for managing depression.
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