The study, published in Nature Mental Health, reveals that individuals who reported feeling lonely were 31 percent more likely to develop dementia compared to those who didn't experience loneliness. The meta-analysis, which examined data from over 600,000 people, claims that loneliness differs from simply being alone; it is an emotional state where an individual lacks desired social connections, making it possible to feel lonely even in the presence of others.
"People can feel lonely even when with others if the quality or quantity of their social connections does not meet what is needed or desired," the researchers wrote. (Related: Dementia found to be the leading cause of death in the U.K. for 2 years in a row.)
Moreover, the study, which reviewed findings from 21 prior studies, identified 13 which showed a significant association between loneliness and increased dementia risk, including links to Alzheimer's disease. The study also revealed that depression and social isolation are the primary factors contributing to loneliness. With these factors, there would be a reduction in social engagement, which could affect one's cognitive health.
"Feeling lonely is also related to reduced engagement in social activities and poor social interactions," the researchers said. "It is plausible that reduced social participation reduces cognitive stimulation, leaving individuals who experience loneliness more vulnerable to cognitive decline."
In a press release published on Oct. 21, Martina Luchetti, the lead researcher of the study, stated that the results are not surprising as she further revealed that the connection between loneliness and dementia starts long before diagnosis.
"Dementia is [sic] spectrum, with neuropathological changes that start decades before clinical onset," said Luchetti, an assistant professor of behavioral sciences at Florida State University College of Medicine. "Loneliness – the dissatisfaction with social relationships – may impact how you are functioning cognitively and in daily life."
Experts agree that loneliness triggers a cascade of physiological and psychological changes that may hasten cognitive decline.
In an interview with the Epoch Times, Mark Mayfield, an assistant professor of counseling at Colorado Christian University, explained the reasons why loneliness is closely linked to cognitive decline. First, he explained that chronic loneliness can heighten stress levels, which, in turn, can impact brain health directly.
"Chronic loneliness triggers prolonged stress, which raises levels of cortisol, a hormone that affects the brain’s cognitive functioning over time," said Mayfield, author of "The Path Out of Loneliness."
"This chronic stress can lead to inflammation and damage areas like the hippocampus and prefrontal cortex, which are essential for memory and executive function."
Mayfield also stated that loneliness often leads to social isolation, which deprives individuals of the mental stimulation crucial to maintaining cognitive health. He emphasized that cognitive health thrives on stimulation derived from social interaction. "Without this, mental agility may deteriorate," Mayfield said.
Another significant factor is depression, which is closely linked to both loneliness and dementia. Depression can be both a cause and effect of loneliness, creating a feedback loop that accelerates cognitive decline. "Loneliness may worsen depressive symptoms, which can contribute to the overall cognitive decline seen in dementia patients," said Mayfield.
Mayfield concluded that loneliness is not just an emotional concern but another significant public health issue. "The study provides scientific backing to the notion that loneliness is not just an emotional state but a public health issue with significant physical and mental consequences, including dementia. This awareness can motivate individuals and caregivers to take loneliness seriously and seek proactive measures."
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