Beneficial effects of black ginseng against particulate matter-induced lung damage
10/09/2020 // Evangelyn Rodriguez // Views

In this study, South Korean researchers investigated the effects of black ginseng extract (BGE) against particulate matter (PM)-induced lung endothelial cell barrier disruption and pulmonary inflammation. Their findings were published in The American Journal of Chinese Medicine.

  • Inhalation of fine particulate matter (PM2.5) is linked to pulmonary injury caused by the loss of vascular barrier integrity.
  • According to studies, black ginseng, which is made by steaming and drying Panax ginseng nine times, exhibits a variety of pharmacological activities, including antibacterial, antihyperglycemic, anti-atopic, antibacterial and anti-inflammatory activities.
  • For their experiment, the researchers examined permeability, leukocyte migration, activation of proinflammatory proteins, generation of reactive oxygen species (ROS) and histology in endothelial cells and mice treated with PM2.5 and BGE.
  • They found that BGE significantly scavenged PM2.5-induced ROS and inhibited ROS-induced activation of p38 mitogen-activated protein kinase (MAPK) while concurrently activating Akt, which helped maintain endothelial integrity.
  • BGE also reduced vascular protein leakage, leukocyte infiltration and proinflammatory cytokine release in the bronchoalveolar lavage fluid in PM-induced lung tissues.

Based on these findings, the researchers concluded that black ginseng protects against PM-induced inflammatory lung injury and vascular hyperpermeability.

Journal Reference:

Lee W, Ku SK, Kim JE, Cho SH, Song GY, Bae JS. INHIBITORY EFFECTS OF BLACK GINSENG ON PARTICULATE MATTER-INDUCED PULMONARY INJURY. The American Journal of Chinese Medicine. 2019;47(06):1237–1251. DOI: 10.1142/s0192415x19500630

Take Action:
Support Natural News by linking to this article from your website.
Permalink to this article:
Embed article link:
Reprinting this article:
Non-commercial use is permitted with credit to (including a clickable link).
Please contact us for more information.
Free Email Alerts
Get independent news alerts on natural cures, food lab tests, cannabis medicine, science, robotics, drones, privacy and more.
App Store
Android App
eTrust Pro Certified

This site is part of the Natural News Network © 2022 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

This site uses cookies
Natural News uses cookies to improve your experience on our site. By using this site, you agree to our privacy policy.
Learn More
Get 100% real, uncensored news delivered straight to your inbox
You can unsubscribe at any time. Your email privacy is completely protected.