A study published in the journal Planta Medica looked at the anti-inflammatory activity of the ethanol leaf extract of Struthanthus vulgaris, the most common medicinal mistletoe plant in Brazil. This study was conducted by a team of researchers from Vila Velha University and the Federal University of Rio de Janeiro in Brazil.
S. vulgaris is used in folk medicine as an anti-inflammatory agent and for cleaning skin wounds.
The research team first examined the anti-inflammatory activity of S. vulgaris in a lab trial on lipopolysaccharide/interferon gamma-stimulated macrophages based on their ability to inhibit nitric oxide production and tumor necrosis factor-alpha.
They also examined the anti-inflammatory activity of S. vulgaris ethanol leaf extract in mice models.
The results of the lab trial showed that S. vulgaris ethanol leaf extract significantly reduced the production of nitric oxide and tumor necrosis factor-alpha in macrophages.
The extract also did not cause any toxic effect.
In mice, S. vulgaris ethanol leaf extract significantly suppressed the influx of leukocytes, mainly neutrophils, protein exudation, nitric oxide, tumor necrosis factor-alpha, and interleukin 1 concentrations in the carrageenan-induced inflammation air pouch.
These results suggested that S. vulgaris ethanol leaf extract has potent anti-inflammatory effects.
Based on these results, the research team suggested that S. vulgaris ethanol leaf extract could be used as a treatment for inflammatory diseases, and that it could be used as a source of anti-inflammatory agents.
Read more studies about medicinal plants with anti-inflammatory effects like S. vulgaris at NaturalMedicine.news.
Marques F, da Costa M, Vittorazzi C, Gramma L, Barth T, de Andrade T, Endringer D, Scherer R, Fronza M. IN VITRO AND IN VIVO ANTI-INFLAMMATORY EFFECTS OF STRUTHANTHUS VULGARIS. Planta Medica. 30 January 2017; 83(09): 770-777. DOI: 10.1055/s-0043-101916