Vinegar made from coconut water has been commonly consumed in some cultures to treat diseases, such as liver disorders and inflammation. In a study published in the journal BMC Complementary and Alternative Medicine, coconut water vinegar was found to help treat liver damage induced by acetaminophen.
A team of researchers from Malaysia and Vietnam looked at the potential benefits of coconut water vinegar in treating liver damage induced by acetaminophen.
For the study, the research team induced liver damage in mice by injecting them with acetaminophen for a week.
One group of mice was given distilled water (untreated), another group received Silybin (positive control), and the third group was given coconut water vinegar.
The treatment with coconut water started seven days after the induction of acetaminophen.
The research team then measured each groups' levels of oxidative stress and inflammation and compared the results.
Results revealed that induction of acetaminophen caused liver damage.
The treatment of coconut water vinegar for two weeks caused reductions in serum liver profiles, liver inflammation, and level of liver cytochrome P450 2E1(CYP2E1). CYP2E1 increases oxidative stress.
In addition, coconut water vinegar improved liver histology and restored liver antioxidants.
These results showed that coconut water vinegar promoted the recovery of liver damage induced by acetaminophen.
In conclusion, the findings of the study indicated that coconut water vinegar can help treat acetaminophen-induced liver damage by restoring antioxidant activity and preventing inflammation.
Mohamad NE, Yeap SK, Beh BK, Ky H, Lim KL, Ho WY, Sharifuddin SA, Long K, Alitheen NB. COCONUT WATER VINEGAR AMELIORATES RECOVERY OF ACETAMINOPHEN INDUCED LIVER DAMAGE IN MICE. BMC Complementary and Alternative Medicine. 25 June 2018; 18(195). DOI: 10.1186/s12906-018-2199-4