Despite the prevalence of hypertension – the Centers for Disease Control and Prevention (CDC) estimates that about one in three Americans has the condition – its specific cause remains largely unknown. It is often attributed to stress but can accompany other underlying conditions, such as kidney disease. What is known are its many complications: Kidney problems, heart attack, stroke, and others.
Hypertension is often treated using maintenance medications that cause a number of side effects, such as dizziness, fatigue, feeling of nervousness, skin rashes, sudden weight loss or gain, and even erection problems in men, among others. These adverse reactions are why many look to natural treatments for possible solutions.
This aforementioned study discussed a promising, safe alternative. Vepris heterophylla, known in Cameroon as Kounikoutchoum, Hohoum, Gougouvetche, and Kotokolhi, is an African herb known traditionally as a treatment for cardiovascular diseases and malaria. Past studies have attested to the cardiovascular benefits of V. heterophylla, but none has looked into the plant's diuretic and antioxidant properties.
The researchers performed their experiment on adult rats, which they divided into several groups. Two groups acted as the positive control and were given diuretic medications furosemide (5 mg/kg) and hydrochlorothiazide (HCTZ, 10 mg/kg). The negative control group received only an equivalent volume of distilled water. Several other groups were tested with 50 mg/kg, 100 mg/kg, 150 mg/kg, 200 mg/kg, and 250 mg/kg of V. heterophylla aqueous extract.
The researchers assessed how much electrolytes the animals lost through their urine in response to the treatment. They also took note of changes in the animals' creatinine, urea, aldosterone, glucose, and albumin in urine and plasma levels. Possible indicators of kidney function and oxidative stress were also tracked.
They found that doses from 150 mg/kg to 250 mg/kg of the aqueous extract caused an increase in eliminated fluids and electrolytes. The phytochemical evaluation also revealed the presence of phenolic compounds, sterols, flavonoids, and alkaloids, suggesting rich antioxidant properties.
Hence, they concluded that V. heterophylla aqueous extract possesses diuretic and antioxidant properties. The researchers believe that the plant deserves further study as a potential treatment for hypertension.
The following home remedies may be used to address high blood pressure and prevent its complications:
Discover how you can prevent hypertension and other precursors of heart disease at Heart.news.
Sources include:
BMCComplementAlternMed.BioMedCentral.com