The study, which was carried out by a team of researchers in China, looked at the ability of the wandering cudweed to treat hyperuricemia and acute gouty arthritis in a mouse model. Hyperuricemia is referred to as the high level of uric acid in the blood, and it is a critical causal factor for the development of many diseases, including gout.
In the study, the research team induced hyperuricemia in mice using potassium oxinate, while acute gouty arthritis was induced by hypodermic injection of 10 milligrams (mg) of monosodium urate (MSU) crystal suspension in paw edema model. After that, they administered wandering cudweed extract to the mice to measure the plant's anti-hyperuricemia activity and xanthine oxidase inhibition.
Researchers found that the extracts from wandering cudweed prevented the production of uric acid and reduced paw swelling. The reduction in the uric acid level in mice with hyperuricemia was due to the regulation of urate transporters, including urate transporter 1 (URAT1), organic anion transporter 1 (OAT1), and renal glucose transporter 9 (GLUT9).
Researchers also found that wandering cudweed extracts exhibited renal protection. Moreover, they found that the main active components of wandering cudweed were 13 caffeoylquinic acid derivatives and one flavone. These phytochemicals both played a role in the inhibition of xanthine oxidase activity and exhibited anti-hyperuricemia properties.
Therefore, wandering cudweed extracts reduced high uric acid levels and prevented gouty arthritis by increasing uric acid excretion and suppressing xanthine oxidase activity and pro-inflammatory cytokines secretion. Based on the findings of the study, the research team deduced that wandering cudweed extracts could be considered as an effective treatment for hyperuricemia and gout.
Here are other natural remedies that may help you control high uric acid levels:
In addition to the natural treatments for hyperuricemia, acupuncture can also help normalize uric acid levels and reduce the risk of gout and kidney damage.
Find out more natural treatments for hyperuricemia by going to AlternativeMedicine.news.