The study, which was conducted by researchers from Denmark, looked at data from more than one million people born between January 1, 1995 and June 30, 2012. From their analysis, the team found that hospitalization for infections was associated with an 84 percent increase in the risk of mental health disorders. They also noted that schizophrenia, obsessive-compulsive disorder, autism, attention-deficit hyperactivity disorder, mental retardation, personality and behavior disorders, oppositional defiant disorder, conduct disorder, and tic disorders had the highest risks after infections. Among the children who developed mental health disorders, they found that 42 percent of them were more likely to be prescribed psychotropic medications. This is very alarming since these drugs have been associated with side effects like suicidal thoughts, problems with coordination, nausea, sleep disorders, and headaches.
For less severe infections that did not require hospitalization, such as bronchitis, the risk of mental illness increased by 40 percent. Meanwhile, the risk of psychotropic medication increased by 22 percent. These results suggest that the severity of infection affects the chances of developing mental health disorders. Additionally, antibiotic use was associated with higher risk of mental illness.
The team also accounted for other factors that could affect the association between infections and mental disorders, such as socioeconomic status and genetics. To do this, they analyzed data on over 800,000 siblings, comparing those who were treated for infections and those who weren't. They found that those who were hospitalized for infections still had a higher risk of mental illness. However, the risk went down from 84 percent to 21 percent.
“The most important take-home message is that there is a close connection between the body and immune system with the brain," said Dr. Kohler-Forsberg, a neuroscientist at Aarhus University Hospital and the lead author of this study. "It is known that specific infectious agents or the inflammatory response may enter the brain from the periphery. This may, in some individuals, result in an increased risk for mental disorders.”
Overall, the results of this study suggest that the immune system plays a role in the development of mental illnesses. This was based on the observed link between infections and the risk of mental health disorders in children.
As parents, it is your responsibility to take care of your children's health. To help you, here are some tips on how you can boost your child's immune system, and consequently protect them from infectious diseases and mental illness.
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