There are more than 100 types of arthritis with all of them having one thing in common, which is the inflammation of the joints. Among the different forms of this condition, the most common one is osteoarthritis, also called the "wear-and-tear" arthritis. The Centers for Disease Control and Prevention estimate that over 30 million adults in the U.S. suffer from this form of arthritis, which commonly affects the hands, fingertips, knees, hips, or spine. The high incidence of osteoarthritis can be attributed to the increasing number of obese individuals and the elderly.
Osteoarthritis occurs when the cartilage that serves as the cushion between joints breaks down, allowing for direct contact between the bones. This condition can progress through five stages from 0, which represents the normal joints, to the most severe stage 4 where there is an extensive or complete loss of cartilage. Patients with the latter stages of osteoarthritis experience symptoms like joint swelling, increased pain, locking or buckling of joints, muscle weakness, and joint deformity that can interfere with their daily activities. Fortunately, it is possible to prevent osteoarthritis progression with proper maintenance and preventive measures.
In this study, which was published in the Journal of Medicinal Food, the researchers extracted fucoidan from brown algae and tested them in male Sprague-Dawley rats with monosodium iodoacetate (MIA)-induced osteoarthritis. Overall, there were 40 rats used in the experiment. These were divided into five groups, with one group serving as the normal model and the rest having MIA-induced osteoarthritis. The groups with osteoarthritis received one of the following treatments for 14 days: conventional osteoarthritis medication (Lyprinol), 50 mg/kg fucoidan, 100 mg/kg fucoidan, or no treatment.
To determine the therapeutic potential of fucoidan, the authors analyzed joint histology and pro-inflammatory cytokine levels in the serum. For the latter, they specifically looked at the concentration of tumor necrosis factor-alpha (TNF-alpha), interleukin 1-beta (IL-1-beta), and matrix metalloproteinase-1 (MMP-1). The results showed that MIA successfully induced osteoarthritis, as exhibited by severe bone loss, cartilage degeneration, and high levels of pro-inflammatory chemicals in the negative control. However, the groups that were treated with fucoidan had few to no problems with their bones and cartilage. Moreover, they also had lower levels of pro-inflammatory cytokines.
The results of this study show that fucoidan alleviates the symptoms of osteoarthritis and it also prevents the potential progression of this condition.
There are many other health benefits that you can enjoy from fucoidan. These include the following:
For more articles about natural remedies for osteoarthritis, visit NaturalCures.news.