To test this theory, the study looked at human mast cell and eosinophilic cell lines. Researchers from Mie University, Shizuoka University, and Iwade Research Institute of Mycology in Japan used an asthma animal model by inducing ovalbumin in mice. The team then fed the mice with either a standard diet or one containing gargal extract.
The team discovered that gargal extract greatly reduced airway hyperresponsiveness, lung eosinophilic infiltration, lung interleukin (IL)-13 expression, and plasma IgE level. At the same time, it substantially increased IL-10 plasma levels and spleen regulatory T cells. The gargal extract treatment also significantly suppressed the expression of cytokines in mast cells and eosinophils compared with control cells.
These results indicated that gargal extract increases the lung population of regulatory T cells and reduces allergic inflammation and airway hyperresponsiveness in mice with allergic bronchial asthma.
Based on the findings, the research team concluded that gargal extract can be an effective natural remedy for allergic bronchial asthma.
Asthma affects approximately 150 million people around the world, and this number is continuously increasing. It also accounts for more than 180,000 deaths in a year. The condition, which often develops during childhood, causes recurring attacks of breathlessness and wheezing. It results in the airways becoming inflamed, making it difficult to breathe. Coughing, shortness of breath, wheezing, and chest tightness are the common symptoms of asthma. While there no drugs available to cure asthma, there are natural ways to treat and control it. (Related: Clinical trials show that acupuncture is an effective treatment for asthma.)
One of these ways is to avoid triggers, which inflame the airways and cause swelling, as well as increased mucus production. Exposure to pollen, chemicals, extreme weather changes, smoke, dust mites, stress, and exercise are common asthma triggers. There are also many food items that you can eat to control asthma attacks. Here are some of them:
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