Extract of a Chinese herb exhibits protective properties against cerebral diseases
07/24/2018 // Edsel Cook // Views

A plant-based compound from the Chinese foxglove (Radix rehmanniae) showed promise as a means of protecting the brain from cerebral diseases. A Chinese study reported that catalpol encouraged the remyelination process that fixed neurological damage caused by multiple sclerosis and other autoimmune disorders.

The study was supported by the Capital Medical University. Its findings were released in the medical journal BMC Complementary and Alternative Medicine.

  • A mouse model was used to simulate human multiple sclerosis. The animals received myelin oligodendrocyte glycoprotein 35-55 (MOG) that caused them to develop experimental autoimmune encephalomyelitis (EAE), which has similar effects to multiple sclerosis.
  • One group of EAE mice was set aside as a negative control. The positive control group was given prednisone acetate, a corticosteroid that is used to treat multiple sclerosis. The rest received either one of three different doses of catalpol (H, M, and L).
  • At the end of the treatment period, the mice were sacrificed. Blood and brain tissue samples were analyzed using different tests to determine the protective effects of the catapol doses.
  • Catalpol treatment boosted neurological functions, prevented inflammatory cells from entering the brain tissue, and stopped demyelination. It also reduced the levels of inflammation-causing T helper 17 (Th17) cells in the blood.
  • The herbal medicine encouraged the production of myelin basic protein that makes up the sheaths of brain cells and the nerve-glial antigen that binds the proteins together. In addition, it improved oligodendrocyte transcription factors 1 and 2 that produced myelin.

Based on their findings, the researchers believed that catalpol could shield the brain tissue of EAE mice and promote the repair of the myelin damaged by multiple sclerosis.

The full study can be reviewed at this link. Or read about more natural ways to prevent viral infections at NaturalMedicine.news.

Journal Reference:

Yang T, Zheng Q, Wang S, Fang L, Liu L, Zhao H, Wang L, Fan Y. EFFECT OF CATALPOL ON REMYELINATION THROUGH EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS ACTING TO PROMOTE OLIG1 AND OLIG2 EXPRESSIONS IN MICE. BMC Complementary and Alternative Medicine. 2017;17(1). DOI: 10.1186/s12906-017-1642-2.



Take Action:
Support Natural News by linking to this article from your website.
Permalink to this article:
Copy
Embed article link:
Copy
Reprinting this article:
Non-commercial use is permitted with credit to NaturalNews.com (including a clickable link).
Please contact us for more information.
Free Email Alerts
Get independent news alerts on natural cures, food lab tests, cannabis medicine, science, robotics, drones, privacy and more.
App Store
Android App
eTrust Pro Certified

This site is part of the Natural News Network © 2022 All Rights Reserved. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. Truth Publishing International, LTD. is not responsible for content written by contributing authors. The information on this site is provided for educational and entertainment purposes only. It is not intended as a substitute for professional advice of any kind. Truth Publishing assumes no responsibility for the use or misuse of this material. Your use of this website indicates your agreement to these terms and those published here. All trademarks, registered trademarks and servicemarks mentioned on this site are the property of their respective owners.

This site uses cookies
Natural News uses cookies to improve your experience on our site. By using this site, you agree to our privacy policy.
Learn More
Close
Get 100% real, uncensored news delivered straight to your inbox
You can unsubscribe at any time. Your email privacy is completely protected.