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Baicalein from Chinese skullcap found to protect the brain against glutamate excitotoxicity

July 01, 2019 -

Based on their findings, the researchers concluded that the biological activity of baicalein in the brain makes it a valuable natural compound that can be used to treat brain disorders related to glutamate excitotoxicity.

Journal Reference:

Chang Y, Lu CW, Lin TY, Huang SK, Wang SJ. BAICALEIN, A CONSTITUENT OF SCUTELLARIA BAICALENSIS, REDUCES GLUTAMATE RELEASE AND PROTECTS NEURONAL CELL AGAINST KAINIC ACID-INDUCED ...

Liver injury caused by heart disease can be reduced by baicalein

July 05, 2019 -

The research team concluded that baicalein can be used to prevent liver injury due to acute myocardial infarction and cardiac surgery.

For more studies on baicalein and alternative medicines for liver damage, visit LiverDamage.news.

Lai CC, Huang PH, Yang AH, Chiang SC, Tang CY, Tseng KW, Huang CH. BAICALEIN REDUCES LIVER INJURY INDUCED BY MYOCARDIAL ISCHEMIA AND REPERFUSION. The American Journal ...

Chinese skullcap can kill brain cancer cells, thanks to its active component baicalein

November 25, 2021 -

In their report, published in The American Journal of Chinese Medicine, the researchers noted that baicalein, a flavonoid derived from the roots of Chinese skullcap, can induce cell autophagy and apoptosis -- two processes that help clear out damaged cells from the body. In particular, the team investigated the mechanism behind the anti-cancer activity of baicalein using human glioma cells.Exploring the anti-cancer activity of baicalein

A ...

Human glioma (cancer) cells can be destroyed with baicalein flavonoid from Scutellaria baicalensis

September 10, 2021 -

In sum, baicalein induced autophagy and apoptosis through the AMPK pathway.

Follow Cancer.news for more natural treatments for cancer.

Journal Reference:

Liu B, Ding L, Zhang L, Wang S, Wang Y, Wang B, et al. BAICALEIN INDUCES AUTOPHAGY AND APOPTOSIS THROUGH AMPK PATHWAY IN HUMAN GLIOMA CELLS. The American Journal of Chinese Medicine. 2019; 47(6): 1405-1418. DOI: 10.1142/S0192415X19500721

This ...

Chinese skullcap can prevent liver injury caused by heart failure

August 19, 2019 -

A team of researchers from the National Yang-Ming University School of Medicine in Taipei, Taiwan looked at the effects of baicalein from Chinese skullcap on liver damage caused by myocardial I/R. For their study, the researchers pretreated rats with three, 10, or 30 milligrams per kilogram (mg/kg) baicalein 10 minutes before they induced myocardial I/R via 40-minute occlusion of the left anterior descending coronary artery and three-hour reperfusion.

The researchers ...

Chinese skullcap protects against brain disorders by preventing neuronal death

October 03, 2019 -

Baicalein can inhibit glutamate release and protect neurons from excitotoxicity

For their study, the researchers used rats to evaluate the effects of baicalein on glutamate release and glutamate neurotoxicity in the hippocampus. The hippocampus is the part of the brain involved in the formation of new memories. It is also associated with learning and emotions. Cell degeneration in the hippocampus is linked to the aging process and the onset of neurodegenerative ...

Study finds Chinese skullcap herb improves bone health

August 27, 2019 -

The particulars of the study

For their study, the researchers used two flavones, namely, baicalin (baicalein 7-O-B- d-glucuronic acid) and its aglycone, baicalein (5,6,7-trihydroxyflavone). They obtained these two compounds from the root extracts of Scutellaria baicalensis, also known as Chinese skullcap. This herb is used in traditional Chinese medicine to treat inflammation, insomnia, hepatitis, epilepsy, atherosclerosis, and cancer. It is also known for its ...

Protect your lungs from ischemia-related injuries with Chinese skullcap

April 11, 2019 -

In the study, the researchers tested the efficacy of baicalein against lung injury caused by myocardial ischemia and reperfusion (I/R). Myocardial ischemia – also referred to as cardiac ischemia – is a condition that occurs when blood flow to the heart is reduced, causing it to pump less efficiently. Reperfusion, on the other hand, is the restoration of blood supply to a vessel previously affected by ischemia. This procedure, in essence, is beneficial for blood vessels ...

Chinese skullcap shown to improve lung injuries caused by myocardial ischemia

April 09, 2019 -

The researchers concluded that baicalein can help with the symptoms of lung injury after being induced with myocardial I/R.

Learn about the other benefits of Chinese skullcap at Herbs.news.

Journal Reference:

Lai CC, Huang PH, Yang AH, Chiang SC, Tang CY, Tseng KW, Huang C-H. BAICALEIN ATTENUATES LUNG INJURY INDUCED BY MYOCARDIAL ISCHEMIA AND REPERFUSION. The American Journal of Chinese Medicine. 2017;45(04):791–811....

Flavones in Chinese skullcap can improve bone mineralization

May 21, 2019 -

Based on these results, the researchers concluded that the baicalin/baicalein encapsulated in Ca-polyP microparticles enhances bone mineralization and the two flavones are good components of nutriceuticals for osteoporosis prevention or bone implants.

Journal Reference:

Wang X-H, Guo Y-W, Tolba E, Kokkinopoulou M, Wiens M, Schröder HC, Müller WE. TWO-ARMED ACTIVATION OF BONE MINERAL DEPOSITION BY THE FLAVONES ...

Scientists look at a traditional Ayurvedic herb as a natural cure for cancer

November 09, 2018 - baicalein. These compounds have shown medicinally important properties, including antibacterial and anticancer properties, which were observed in chrysin and baicalein. In addition to these, extracts from the Indian trumpet flower were also observed to induce cell death.

In this study, which was published in BMC Complementary and Alternative Medicine, the researchers conducted an in vivo test for determining anti-oxidant activity of leaf extracts from ...

Chinese skullcap herb found to kill ovarian cancer cells

September 17, 2019 -

The health benefits of Chinese skullcap

S. baicalensis belongs to the mint family and is widely known as a rich source of antioxidants. In particular, the flavones found in S. baicalensis can significantly reduce the effects of oxidative stress on many tissues in the body. Its major active components, baicalin and BA, are also known to display a wide range of therapeutic activities.

In traditional medicine, S. baicalensis is used to treat ailments related to the heart, ...

The science behind herbal remedies: Study identifies the genes responsible for Chinese skullcap’s health benefits

October 03, 2019 - baicalein can help to protect nerve cells against the damage caused by the disease.

Prostate cancer

One study illustrated how the compounds in skullcap can slow prostate cancer tumor growth. It can also stop the development of benign prostatic hyperplasia through its ability to relieve inflammation and suppress abnormal androgen.

Traditional Chinese Medicine has been gaining new respect after Professor You-you Tu was awarded the Nobel prize for Physiology ...

Yes, you can detox from covid “vaccine” spike proteins: here’s how

February 17, 2022 -

The worldwide coalition of health-focused organizations and civil society groups recommends the following substances for inhibiting covid injection spike proteins throughout the body:

Prunella vulgaris

Emodin

Dandelion leaf extract

Pine needles

Neem

Ivermectin

Ivermectin in particular docks to the SARS-CoV-2 spike receptor-bending domain attached to ACE2, which may block spike proteins from attaching to the human cell membrane.

The following ...

Organic functional mushrooms: best immune-boosting medicine from Mother Nature

March 30, 2022 - baicalein that promote immune system health by reducing inflammation and stimulating the release of protective compounds.Shiitake mushroom

This mushroom is tan to dark brown in color, have broad umbrella-shaped caps, wide open veils, tan gills and curved stems that should be removed. Shiitake mushrooms are the most common edible, medicinal fungi and one of the most valuable, both nutritionally and flavor-wise. Shiitakes have a meaty texture and are rich in savory ...