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Dietitian discusses 4 health benefits of fasting


Fasting triggers autophagy Fasting triggers autophagy. This process is your body’s cellular recycling system. ... Scientists are looking into autophagy’s role in potentially preventing and fighting disease. "...

Surprising new study may help scientists stop cancer from occurring in the first place


While both autophagy and apoptosis contributed to the death of a small number of normal cells, the researchers found that autophagy was the primary cause of cell death during crisis. Damaged or missing telomeres trigger autophagy in pre-cancerous cells Karlseder and Nassour went on to test the consequences of stopping autophagy during crisis. "...

Functional foods are healthy, but why?


They focused particularly on how these mechanisms are related to autophagy, as dysfunctional autophagy has been linked to the onset of many chronic or age-related diseases. Autophagy and chronic diseases Metabolism is a crucial part of autophagy and serves as a regulatory factor for three vital sources of energy for cells, namely glucose , fats and protein. "...

A breakthrough in understanding how inflammation in the colon works could lead to cancer prevention


Nevertheless, autophagy can be managed through good nutrition. Natural compounds in fruits and vegetables activates autophagy and helps prevent inflammation and alleviate the symptoms of gut diseases. ... Help autophagy help you Generally, autophagy is boosted by intermittent fasting and caloric restriction. "...

Simple strategies that activate your body's natural detoxification process


The benefits of autophagy Here are some of the health benefits that autophagy offers: - Removes toxins – Because autophagy encourages the immune system to eliminate foreign invaders in the body, it effectively removes all kinds of harmful substances that could cause inflammation and damage to cells. ... Other ways to induce autophagy Autophagy can also be activated through the intake of certain foods, herbs, and supplements . "...

Plants starved for energy found to resort to “self-cannibalism” by breaking down and consuming cells from their own leaves for survival


In a previous report, researchers had already shown how plant chloroplasts are digested using autophagy when the host plant is starved for energy. ... Autophagy isn’t just limited to plants – it also occurs in fungi, slime mold, nematodes, fruit flies and insects, rodents, and humans. "...

Nutrition is the key to keeping your cells young: When cells don't get enough energy they breakdown, creating conditions for many age-related diseases


The experts also note that autophagy takes place when energy gets depleted or during hunger. ... Autophagy declines over time, animal study finds An animal study published in the eLife journal has revealed that autophagy may show a significant decline as the body ages. "...

Functional foods help fight disease on a cellular level, thanks to bioactive ingredients


What is autophagy? Autophagy is the body’s way of cleansing itself. It is an evolutionary conserved cellular process of removing aberrant components in eukaryotic cells. ... A problem in the process of autophagy means problems for the whole body. Conversely, an enhanced status of autophagy can be beneficial for treating chronic diseases . "...

Dietary restrictions may help you live longer, according to a new study


The process of autophagy, also known as cellular recycling, plays a crucial role in lifespan expansion. ... Furthermore, turning off autophagy caused the worms to move around less. The researchers believe this to be an indication of autophagy’s impact on other organs in the worms’ body. "...

Boost cellular health with the immortality herb


Because of this, eliminating these substances via autophagy is crucial for the body to maintain good health. ... The researchers also reported that DMC can simultaneously induce cell autophagy. "...

Human glioma (cancer) cells can be destroyed with baicalein flavonoid from Scutellaria baicalensis


If phosphorylation of AMPK was inhibited, autophagy and apoptosis were also inhibited. ... BAICALEIN INDUCES AUTOPHAGY AND APOPTOSIS THROUGH AMPK PATHWAY IN HUMAN GLIOMA CELLS. "...

Researchers identify betulinic acid as a promising new agent for treating hepatic fibrosis


Autophagy is a cell-regulated process of clearing out unnecessary or damaged cellular components . ... LC3 plays a central role in autophagy. Meanwhile in vitro, betulinic acid also increased the expression of the autophagy marker, LC3II, but decreased the expression of alpha muscle actin in hepatic stellate cells. "...

Scutellaria Radix found to be a promising anti-cancer agent against non-small cell lung cancer


The researchers reported that SR treatment caused an increase in the ratio of autophagy-related proteins LC3-II and LC3-I in NSCLC cells, which suggested that SR treatment induces autophagy. In contrast, co-treatment with 3-methyladenine (3-MA), an inhibitor of autophagy, led to the loss of autophagy and the suppression of apoptosis. "...

Betulinic acid found to demonstrate anti-hepatic fibrosis activity


Based on their findings, the researchers concluded that the anti-hepatic fibrosis activity of betulinic acid is due to its ability to induce autophagy, which makes it a promising new agent for treating liver fibrosis . ... BETULINIC ACID ATTENUATES LIVER FIBROSIS BY INDUCING AUTOPHAGY VIA THE MITOGEN-ACTIVATED PROTEIN KINASE/EXTRACELLULAR SIGNAL-REGULATED KINASE PATHWAY. "...

Nicotinamide protects hepatocytes from palmitate-induced cell death


The results of their study were published in the journal Nutrition Research. - Lipotoxicity induced by saturated fatty acids contributes to the development of non-alcoholic fatty liver disease (NAFLD); however, the exact mechanism behind this remains unclear. - Palmitate is the most abundant saturated fatty acid in the circulation and a major lipotoxic inducer. - Research suggests that autophagy induction is protective against palmitate-induced cell death in a variety of cell types, including ...

The role of functional foods in treating chronic diseases


They believe this review could serve as a reference or provide novel ideas for the development of functional foods capable of modulating autophagy for the treatment of chronic diseases. ... AUTOPHAGY-ASSOCIATED SIGNAL PATHWAYS OF FUNCTIONAL FOODS FOR CHRONIC DISEASES. Food Science and Human Wellness. "...

Investigating the apoptopic and autophagic effects of Scutellaria Radix in non-small cell lung cancer


This suggested that SR treatment induces autophagy in NSCLC cells. - In contrast, co-treatment with 3-Methyladenine (3-MA) led to the loss of autophagy and the suppression of apoptosis. ... SCUTELLARIA RADIX PROMOTES APOPTOSIS IN NON-SMALL CELL LUNG CANCER CELLS VIA INDUCTION OF AMPK-DEPENDENT AUTOPHAGY. "...

Anti-inflammatory omega-3 fatty acids may help stave off conditions linked to aging like Alzheimer's and heart disease


In one study, published in the journal Autophagy, Norwegian and American researchers found that omega-3 fatty acids increase autophagy in immune cells called macrophages . ... The researchers hypothesized that omega-3 fatty acids lower inflammation by elevating autophagy in macrophages. "...

Strict eating and fasting schedule cleans the blood: Study finds it could clear out proteins that cause Huntington’s disease


The fasting triggered a process called autophagy, in which the cells clean themselves, removing damaged and unnecessary components. ... The exact location of the cleavage site would seem to be key to the autophagy process. "...

Resveratrol can help treat alcoholic fatty liver disease


Autophagy is a vital physiological process in cellular catabolism that involves the regulation of lipid droplets. ... It also increased the number of autophagosomes and promoted the formation of autophagy, as well as the levels of protein light chain3- II (LC3-II) and Beclin1 – both of which play a role in the regulation of autophagy. "...