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Apoptosis news, articles and information:

a long time ago - Apoptosis news, articles and information:

Research suggests chlorella may have apoptotic anticancer effects

Concepts related to Apoptosis

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Cell apoptosis news, articles and information:

a long time ago - Cell apoptosis news, articles and information:

Concepts related to Cell apoptosis

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Probiotic yeast induces apoptosis in colon cancer cells

July 04, 2019 -

In sum, P. kudriavzevii AS-12 secretion metabolites exhibited anti-cancer effects in colon cancer cells.

Journal Reference:

Saber A, Alipour B, Faghfoori Z, Jam AM, Khosroushahi AY. SECRETION METABOLITES OF PROBIOTIC YEAST, PICHIA KUDRIAVZEVII AS-12, INDUCES APOPTOSIS PATHWAYS IN HUMAN COLORECTAL CANCER CELL LINES. Nutrition Research. 2017;41:36–46. DOI: 10.1016/j.nutres.2017.04.001

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Can curcumin induce apoptosis in colon cancer cells?

February 22, 2019 -

Overall, these results suggest that curcumin has potential use as a natural remedy for colon cancer. This is possible because of its ability to generate ROS that can induce apoptosis and inhibit the cell cycle of colon cancer cells.

Read more articles on the health benefits of curcumin at Turmeric.news.

Journal Reference:

Agarwal A, Kasinathan A, Ganesan R, Balasubramanian A, Bhaskaran J, Suresh S, Srinivasan R, ...

Curcumin inhibits pituitary tumor cell proliferation, induces apoptosis

December 10, 2013 - Curcumin inhibits pituitary tumor cell proliferation, induces apoptosis

Tuesday, December 10, 2013 by: PF LouisTags: curcumin, pituitary tumors, apoptosis

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Sulforaphane found to trigger apoptosis in human colon cancer cells

July 01, 2019 -

Based on these findings, the researchers concluded that SFN is a novel anticancer agent that can be used to treat human colon cancer in the future.

Journal Reference:

Liu KC, Shih TY, Kuo CL, Ma YS, Yang JL, Wu PP, Huang YP, Lai KC, Chung JG. SULFORAPHANE INDUCES CELL DEATH THROUGH G2/M PHASE ARREST AND TRIGGERS APOPTOSIS IN HCT 116 HUMAN COLON CANCER CELLS. The American Journal of Chinese ...

Beach vitex fruit can induce apoptosis in human colorectal cancer cells

May 02, 2019 -

Based on these findings, the researchers conclude that V. rotundifolia induces apoptosis in human colorectal cancer cells by activating ATF3 expression through transcriptional regulation and subsequently suppresses Bcl-2 expression as an anti-apoptotic protein.

Visit AntiCancer.news for more studies on anticancer compounds found in medicinal plants.

Journal Reference:

Song HM, Park GH, Koo JS, Jeong HJ, Jeong ...

Traditional Chinese herbal medicine, insect tea, found to be a potential treatment for cancer

October 10, 2018 - apoptosis or programmed cell death. Apoptosis is an important process that allows the body to get rid of dysfunctional cells and maintain the balance between new and old, damaged cells. Like normal cells, cancer cells may be stimulated to “die” naturally. Stimulating apoptosis through food components is, therefore, seen as one of the most effective ways to effectively and safely treat cancer.

The researchers cultured HepG2 human liver cancer ...

The apoptotic and anticancer effects of cinnamon

September 03, 2024 - apoptosis can lead to dangerous conditions including Alzheimer's and Parkinson's disease, while too little apoptosis can lead to the uncontrolled growth of abnormal cells (cancer).[iii]

Cancerous cells are usually able to avoid apoptosis, allowing them to survive and grow rapidly. The pro-apoptotic activity of cinnamon makes it a potential inhibitory measure against cancer cell growth.[iv] Researchers have concluded that there are three ways ...

TCM herb Ku Shen found to be an effective natural treatment for leukemia

August 29, 2019 -

Researchers from the Chang Gung University of Science and Technology in Taiwan looked at the ability of sophoraflavanone G to induce programmed cell death (apoptosis) in human leukemia cells. One of the most widely studied topics, apoptosis has a role in both the development and treatment of various cancers, including leukemia. If a cell experiences a disruption in apoptosis, it increases the likelihood of it being transformed into a malignant (and ...

Beach vitex herb found to possess anticancer properties, according to study

May 16, 2019 -

The fruit of V. rotundifolia, commonly known as beach vitex, has been reported to induce apoptosis in human colorectal cancer cells through the accumulation of oxygen species. The researchers aimed to understand further the mechanism by which V. rotundifolia induces apoptosis even though the molecular target for apoptosis has already been established.

In the study, the researchers determined a new potential mechanism for the relationship between V....

TCM herbal formula makes resistant cancer cells susceptible to effective treatments

February 16, 2022 - apoptosis (programmed cell death) in gastric cancer cells by promoting the translocation of cofilin-1. Cofilin-1 is a protein that plays an important role in the development of MDR by cancer cells. The researchers found that mitochondrial translocation of cofilin-1 subsequently leads to the activation of the mitochondrial apoptosis pathway.

To continue their evaluation of ZJW, the researchers constructed a gastric cancer cell model using samples derived ...

Can this summer lawn weed help protect you from cervical cancer? Researchers say YES

June 23, 2020 - apoptosis (programmed cell death) in DCs, tumor cells avoid recognition and escape immune system surveillance. This is why the number of DCs can determine how favorable the prognosis is for cancer patients.

To investigate the mechanism behind POL-P3b's anti-cancer activity, the researchers first isolated intestinal dendritic cells from tumor-bearing mice treated with 50?mg/kg, 100?mg/kg and 200?mg/kg POL-P3b. They then evaluated the effects of POL-P3b on the proliferation ...

Kamikaze immune cells: Bacteria infected cells die off quickly to sound the back-up alarm against stealthy invaders

October 12, 2017 - apoptosis, a form of cell death commonly occurring in multi-cellular organisms.

In this study, Brodsky's team discovered that humans and mice can survive Yersinia infections because of their similar immune systems.

To understand how host cells overcome this pathogen, Brodsky's team focused on the activity of an enzyme called RIPK1. RIPK1 was known to play a key role in signaling cell death in response to tissue damage and pathogen recognition.

"RIPK1 ...

Anti-parasite benzimidazole drugs show promise for treating cancer, but remain SUPPRESSED by the FDA

October 13, 2023 - apoptosis of both parasites and cancer cells.

The researchers did however find that benzimidazole drugs have low water solubility, making them hard to apply in clinical applications. This has led researchers to combine the drug with nanoparticles for more effective applications in vivo. There are currently no clinical trials for Fenbendazole, yet there are clinical trials for a similar drug in this class, called Mebendazole. This drug is showing promise as an adjuvant ...

Traditional Chinese Medicine monomers offer hope for SAFER cervical cancer treatments

September 27, 2024 - apoptosis – making them effective in both laboratory (in vitro) and animal (in vivo) models of cancer.Cinnamaldehyde

Extracted from cinnamon, cinnamaldehyde has emerged as a promising anticancer agent. Research showed that in mouse models of cervical cancer, cinnamaldehyde blocked the P13K/Akt signaling pathway, inhibiting tumor growth and improving overall health. Doses of 60 mg/kg and 240 mg/kg administered for 14 days significantly reduced tumor development ...

Hope for arthritis sufferers: Researchers identify a chemical that can stop inflammatory cell death

July 13, 2020 - apoptosis.

Necrosis pertains to cell death caused by a disease, infection or cell injury. Apoptosis, on the other hand, refers to programmed cell death.

In apoptosis, cells undergo a kind of “cellular suicide”. The cell is first fragmented into smaller pieces, and the resulting debris is then left for immune cells called phagocytes to get rid of.

Apoptosis is an important process since it helps eliminate pre-cancerous cells, ...

Scientists study Canadian medicinal plants to explore natural cures for diabetes

December 23, 2018 - apoptosis is hardly a good thing. In diabetes, the cells go through apoptosis at an abnormal rate. It usually starts with the death of the pancreatic beta cells, the cells responsible for producing the hormone insulin. The insufficiency in insulin results in a jump in blood glucose levels, which leads to more cellular death. Apart from kidney cells, those in the liver and the nervous system are also at a considerable risk.

DN is one of the most common ...

12 Potent ANTICANCER agents found in edible plants

January 30, 2024 -

Hallmark features of cancer include the ability to evade apoptosis (programmed cell death), induce angiogenesis (the growth of new blood vessels that tumors need to grow), replicate limitlessly, produce growth signals that are self-sufficient, be insensitive to anti-growth signals, invade nearby tissue and metastasize (spread to another part of the body).

Fortunately, studies show that naturally occurring bioactive compounds from plants, also known as phytochemicals, ...

Sulforaphane, a compound in cruciferous vegetables, found to kill colon cancer cells

October 08, 2019 - apoptosis, and the generation of reactive oxygen species (ROS) and Ca2+. It also increased the activities of caspase-8, -9, and -3 in HCT 116 cells but reduced mitochondrial membrane potential.

G2/M refers to the transition phase during the cell cycle that occurs between the G2 (gap 2) phase and the M (mitosis) phase. G2/M serves as a checkpoint that controls the phase progression of the cell cycle and regulates the quality and rate of cell division. Defects in ...