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Here’s why eating garlic and onions can prevent hypertension and diabetes

April 16, 2021 -

In a recent study, researchers at the Federal University of Technology in Nigeria investigated the benefits of eating garlic, white onion and purple onion against serious conditions like diabetes and hypertension. They confirmed these by looking at how extracts from the three alliums affect the activity of diabetes-related enzymes, such as a-amylase and a-glucosidase, and the hypertension-related enzyme, angiotensin-converting enzyme (ACE).

The researchers reported ...

Molecule in Nigella sativa (black seed) may prevent spike protein-induced vascular damage, scientists conclude in published paper indexed by NIH (updated)

July 27, 2021 -

Researchers out of India investigated the effects of nigellidine, an indazole alkaloid of black seed, using molecular docking for binding to different angiotensin-binding proteins, as well as the spike glycoprotein. They found that nigellidine "strongly binds" to the spike protein at what is known as the hinge region or active site opening, which may in turn hamper its binding to ACE2 receptor surfaces.

"Nigellidine effectively binds in the Angiotensin-II ...

Certain compounds in milk can protect against hypertension – study

July 12, 2019 -

The research team, in particular, looked at earlier studies that highlight the ACE-inhibiting properties of certain milk proteins. ACE – short for angiotensin I-converting enzyme – transforms angiotensin I to angiotensin II, a protein hormone known to increase blood pressure, body water, and sodium content. Having too much angiotensin II in the body can cause high blood pressure (hypertension). It can also lead to heart failure, as the protein ...

Prenatal high-salt diet leads to complications in offspring

March 01, 2019 -

In conclusion, the findings of the study suggest that prenatal high-salt diet damages nitric oxide-mediated vasodilatation by increasing oxidative stress, which also impairs the renin-angiotensin system.

To read more studies on the causes of heart disease, visit HeartDisease.news.

Journal Reference:

Liu Y, Qi L, Wu J, Xu T, Yang C, Chen X, Lv J, Xu Z. PRENATAL HIGH-SALT DIET IMPAIRED VASODILATATION WITH REPROGRAMMED ...

Powerful natural medicine: Black cumin remedies kidney damage

December 03, 2018 - angiotensin into several forms, part of the actions of which is to constrict surrounding capillaries increasing the pressure of blood that enters the kidneys.

However, this effect, meant to maintain optimal kidney function, damages the kidneys in the long run. Chronic high blood pressure negatively affects the kidneys and is one of the causes of kidney damage. Blocking the renin-angiotensin system is, therefore, one of the main methods both for regulating ...

Animal study shows that Rosmarinic acid can reduce hypertension symptoms and skeletal muscle glucose transport in mice

June 12, 2020 - angiotensin I, which is converted into such by an enzyme known as angiotensin-converting enzyme (ACE). Because of the consequence of its activity, chemicals that inhibit ACE are used for the treatment of hypertension because they can help relax the veins and arteries. This results in the lowering of blood pressure.

For their study, the researchers evaluated the effects of short- and long-term treatment with rosmarinic acid on blood pressure and glucose transport ...

Be warned: Crash dieting may give you more belly fat

December 13, 2018 - angiotensin II hormone was also more potent at increasing blood pressure in the rats that followed a reduced-calorie diet. Angiotensin II increases blood pressure by binding to receptors and constricting blood vessels. In addition, it promotes the production of other hormones that cause the body to retain salt and water.

This elevated blood pressure, when combined with increased belly fat, could lead to chronic health conditions for people who have crash-dieted ...

Exercise is still the best way to lower blood pressure, study shows

April 19, 2019 -

In a recent study, researchers from the U.K. and the U.S. pooled data from existing studies to compare the effectiveness of exercise in lowering systolic blood pressure (SBP) with that of commonly prescribed antihypertensive medications. These medications included angiotensin-converting enzyme inhibitors (ACE-I), angiotensin-2 receptor blockers (ARBs), beta-blockers, calcium blockers, and diuretics. They targeted SBP because people with high SBP are at great ...

Bioactive milk peptides found to have anti-hypertensive properties

June 26, 2019 -

In sum, the researchers recommend exploring milk di- and tripeptides for use in functional food, as well as a natural alternative to ACE inhibitor drugs.

Explore the science of natural food at FoodScience.news.

Journal Reference:

Vukic VR, Vukic DV, Milanovic SD, Ilicic MD, Kanuric KG, Johnson MS. IN SILICO IDENTIFICATION OF MILK ANTIHYPERTENSIVE DI- AND TRIPEPTIDES INVOLVED IN ANGIOTENSIN I–CONVERTING ENZYME INHIBITORY ...

Exploring the vasolidatory benefits of Rosmarinic acid

June 08, 2020 -

Based on these findings, the researchers concluded that rosmarinic acid treatment is an effective alternative strategy for improving skeletal muscle glucose transport and protecting against ANG II-induced hypertension and hyperglycemia.

Read the full study at this link.

Journal Reference:

Prasannarong M, Saengsirisuwan V, Surapongchai J, Buniam J, Chukijrungroat N, Rattanavichit Y. ROSMARINIC ACID IMPROVES ...

These 16 pharmaceutical drugs are made from animal venom

April 17, 2022 - angiotensin-converting enzyme (ACE) inhibitor drug made from the venom of the jararaca pit viper snake (Bothrops jararaca)

• enalapril (VASOTEC), another angiotensin-converting enzyme (ACE) inhibitor drug made from the venom of the jararaca pit viper snake (Bothrops jararaca)• exenatide (BYETTA), a glucagon-like peptide-1 receptor agonist drug made from the venom of the Gila monster lizard (Heloderma suspectum)

• exenatide (BYDUREON), an extended release ...

Millions of patients are being OVERDOSED with blood pressure medication, study reveals

June 13, 2017 - angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers, beta blockers, calcium channel blocker, and thiazides — were included in the review.

When the researchers compared the effectiveness of quarter-dose therapy to both a standard dose or placebo, they found that taking a quarter-dose of one medication did not lower blood pressure as much as a full dose did. However, the team discovered that the combination of two medications in a quarter ...

Who needs meds? Simple potassium may lower blood pressure more safely than prescription drugs

April 13, 2017 - angiotensin system and decrease angiotensin markers on vascular, adrenal, or renal receptors. Researchers also found that dietary potassium helps reduce blood pressure levels by relaxing vascular smooth muscles and curbing peripheral vascular resistance.

In contrast, a 2010 study found that using antihypertensive drugs to lower blood pressure levels may do more harm than good. Researchers said various antihypertensive drugs were found to induce different ...

Turmeric’s golden elixir: Ancient wisdom validated by science for blood pressure wellness

May 13, 2025 - angiotensin II-driven hypertension by downregulating the renin-angiotensin-aldosterone system (RAAS), a key target in antihypertensive medications (Wang et al., 2023).Unlocking turmeric’s potential: Synergy in diet and formulation

Curcumin’s therapeutic potential hinges on optimal absorption. Only 1–5% of oral doses enter systemic circulation due to rapid metabolism by the liver and poor water solubility. To enhance uptake, traditional wisdom—marrying turmeric ...

Meet the “two-day cure” plant: An African medicinal plant that can naturally lower blood pressure

August 19, 2019 - angiotensin II levels. Additionally, they quantified mineralocorticoid receptor concentration in the kidney homogenate.

The researchers found that S. serratuloides hydroethanolic extract treatment significantly and dose-dependently lowered blood pressure, low-density lipoprotein (LDL) cholesterol, and triglyceride levels of the rats. It also dramatically prevented L-NAME-induced decrease in blood pressure regulators such as angiotensin II, high-density ...

Give your aging body a break: Older adults should avoid a high-salt diet

June 06, 2018 - angiotensin type 1 (AT1) receptors that are activated once it binds with angiotensin II, the peptide hormone. Earlier studies have shown that aldosterone levels decrease with age and it becomes less responsive to environmental changes. (Related: Natural remedies treat adrenal fatigue.)

The researchers studied the effects of aldosterone and animal response to dietary sodium by administering a low-sodium diet to young and old rats. At the start of the study, old ...

Scientists find that the coronavirus has another doorway to infect human cells

November 18, 2020 - angiotensin-converting enzyme 2, or ACE 2 receptor. This receptor normally modulates the many activities of a protein called angiotensin 2, which affects blood pressure and inflammation. SARS-CoV-2 uses spike proteins to attach to protein receptors of human cells, such as ACE 2.

But the two research teams noticed that a tiny piece of the spike protein was similar to regions of human protein sequences that were known to bind to neuropilin receptors. With ...

Blood-Pressure Drugs Linked to Birth Defects (press release)

July 28, 2006 - angiotensin-converting enzyme) drugs during the entire pregnancy."We found there was a three-fold increased [overall] risk of birth defects to infants whose mothers took ACE inhibitors the first trimester, compared to infants whose mothers took no blood-pressure medication," said study lead author Dr. William O. Cooper, associate professor of pediatrics at Vanderbilt University School of Medicine.The study findings appear in the June 8 issue of the New England ...

Ibuprofen may increase susceptibility to the coronavirus, new study says; experts also link infectious complications to its use

March 23, 2020 - angiotensin-converting enzyme 2 or ACE2 also increase the risk of severe coronavirus infection.

https://twitter.com/olivierveran/status/1238776545398923264

ACE2 is a protein produced by cells that cover the surfaces of major organs, such as the skin, the intestines, the kidneys and the lungs. These cells also serve as the outer lining of blood vessels. Previous studies have found that ACE2 acts as a receptor on the surfaces of these cells, and human pathogenic ...

Moms, take care of your diet: Eating a lot of salty foods while pregnant can increase the risk of your child having a cardiovascular condition

March 28, 2019 - angiotensin system, a hormone system that regulates blood pressure and fluid balance.

These results indicate that high intake of salt during pregnancy can increase oxidative stress and damage blood vessels, which can lead to an increased risk of the child having a cardiovascular disease. The findings of the study provide new information for understanding and early prevention of cardiovascular diseases in fetal origins.Foods that are high in salt

High amounts ...