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CONFIRMED: Exposure to aldehyde chemicals found to trigger the degradation of BRCA2 breast cancer genes in women

June 11, 2017 - aldehyde exposure impedes DNA repair in all cells, even the healthy ones, people who have inherited a faulty copy of the BRCA2 gene are particularly sensitive to such damage.

To seek an answer to the question whether aldehyde exposure could promote cancer, Ashok Venkitaraman, PH.D., director of the Medical Research Council Cancer Unit at the University of Cambridge, and his team examined genetically engineered human cells and cells from women bearing a faulty ...

Olive oil really is the healthiest oil for frying foods, scientists find

July 05, 2017 - aldehydes when the oils reach their smoking point during high heat cooking. While aldehydes are naturally-occurring compounds, past research revealed that aldehyde accumulation in the body may lead to adverse health conditions including cancer and diabetes.

In an effort to determine the amount of aldehydes produced during frying, a team of researchers at the University of the Basque Country analyzed olive, sunflower, and flaxseed oils that ...

From bad to worse: What are the side effects of mixing alcohol and antibiotics?

November 14, 2019 -

Nausea is a side effect shared by antibiotics and alcohol. People who take pharmaceutical drugs grow queasy because the harsh chemicals affect their gastrointestinal system.

Drinkers, on the other hand, experience nausea from acetaldehyde, the toxic byproduct produced when the liver breaks down alcohol. Alcohol also interacts with some classes of antibiotics.

Tetracyclines get prescribed for many bacterial infections. This class of antibiotics includes ...

Novel chemistry method paves the way for large-scale production of bioplastic bottles

February 28, 2019 - aldehyde groups. Acetalization attaches a chemical side chain to these volatile aldehyde groups, turning them into aldehydes that will not be affected by other reactions.

When HMF undergoes acetalization, it turns into HMF-acetal. The aldehydes in this new organic compound are much more stable than their precursor; they will not be triggered by the side reactions during the oxidation process.

The new process uses 1,3-propanediol ...

Orange oil makes a great natural preservative: It prevents foodborne pathogens and extends shelf life

June 06, 2019 - aldehyde, and ketone. These can alter the flavor of a food product or produce off-putting odors. In the study, the researchers stressed the need for natural antioxidants, given synthetic ones like butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) have been linked to severe side effects.

The findings revealed that folded orange oil had the best results in terms of antimicrobial activity against all foodborne pathogens. Twenty times-folded orange oil, ...

The bark of this rainforest tree from Australia inhibits the growth of pathogenic bacteria

January 30, 2019 - aldehyde, that are associated with antibacterial activities. Unfortunately, there are limited studies on the antibacterial potential of its leaves.

The goal of this study, which was published in the journal Pharmacognosy Communications, was to evaluate the antibacterial activity of Oliver's sassafras and identify the compounds that potentially contribute to this effect. To do this, the researchers first collected extracts from dried and powdered leaves of the tree ...

Stunned scientists confirm drug-resistant breast cancer cells can be effectively treated with citral, a chemical found in lemongrass

September 27, 2018 - aldehyde dehydrogenase positive cells, which have been linked with drug-resistance, can be inhibited. Less number of cells were observed for the secondary spheroids. This means that ability of drug-resistant cells to self-renew was reduced.

Lastly, quantitative real time-PCR and western blot were performed to determine the potential mechanism for citral effect. These experiments look into the genes that are expressed in the citral-treated cancer cells. Based on ...

Olive and mastic trees have compounds that help improve oral health

September 11, 2019 - aldehyde. They evaluated the activity of these compounds against the following bacteria:

The first eight bacterial species are commonly found in the oral cavity, while the last two are reference bacteria that can be found in the intestine and the skin, respectively.

The researchers found that among the compounds isolated from olives, maslinic acid is the most effective against oral streptococci and anaerobic ...

Contaminated air in commercial aircraft is poisoning passengers and crew

January 18, 2019 - aldehyde.

These heated lubricants make their way into passenger cabins when bleed air is used, and they create toxic vapors. Wet seals are in place to keep the oil and air apart, but they lose their efficacy over time and are often improperly maintained. When they fail suddenly, it causes oil vapors to make their way into bleed air in what are known as “fume events,” and those in the cabin may note a blue-tinged smoke with a foul smell. Because there are no sensors ...

Why is cilantro so good for the brain? Science explains

July 30, 2020 - aldehyde (E)-2-dodecenal, activates several potassium channels in the brain. These channels are part of the voltage-gated potassium channel subfamily Q (KCNQ), which can be found in neurons. According to previous studies, KCNQ dysfunction can lead to severe, treatment-resistant epileptic seizures.

The researchers also found that (E)-2-dodecenal could delay chemically-induced seizures, suggesting its involvement in cilantro's anti-convulsant activity. Geoffrey Abbott, ...

Food supplements can play a big role in enhancing muscle detoxification in athletes

May 15, 2020 - aldehydes to form adducts, or addition products, whose presence showed that carnosine was actively battling the harmful aldehydes.

"The carnosine found in the athletes’ muscles demonstrates the beneficial effect of physical exercise, since it causes the elimination of toxic substances," said Marisa Helena Gennari de Medeiros, Full Professor at IQ-USP and last author of the study.

The scientists took samples of outer thigh (vastus lateralis) muscle ...

Suicide, with benefits: Bizarre tech startup pitches “brain up-load” that kills you in the process

April 19, 2018 - aldehyde-stabilized cryopreservation. The procedure took roughly six hours and the brain was cut into paper-thin sheets so it could be imaged with an electron microscope. They effectively demonstrated they can preserve an entire brain at the nanometer level, detailing the entire web of synapses that connect neurons. By detailing this connectome, including billions of brain cells and the thousands of neurons that interact with one another, Nectome can bring a dead brain back ...