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Coffee nap: The brain benefits of combining caffeine with sleep

July 19, 2023 - adenosine, which promotes sleepiness. Because caffeine and adenosine are structurally similar, caffeine molecules can block the function of adenosine by binding to the same receptors in your brain.

Normally, adenosine slowly accumulates in your brain throughout the day and is cleared at night while you sleep. But research has found that when you're sleep-deprived, the adenosine levels in your basal forebrain, a brain region that's crucial for ...

Study finds INSUFFICIENT SLEEP negatively impacts cardiovascular health

October 25, 2023 - adenosine (a byproduct of cellular metabolism) in the brain. The more active and alert you are during the day, the more adenosine builds up and eventually leads you to "feel sleepy."

Practice these healthy sleep tips:

Continuous sleep deprivation can cause reduced performance and detrimental effects on both your physical and psychological health and well-being.

Visit for more stories about the ...

Sweet and deadly: Here’s how SUGAR fuels CANCER in the body

December 05, 2023 - adenosine triphosphate (ATP) – which is produced by breaking down glucose in a complex process called glycolysis.

According to the National Institute of Environmental Health Sciences, healthy, normal cells typically grow and multiply in a controlled way to replace old or dead cells. Some cells become cancer cells when they do not follow this cycle – instead of dying as they should, they grow and multiply uncontrollably, regardless of whether new cells are needed ...

Enjoy that cup of joe: Here are some science-backed health benefits of CAFFEINE

June 13, 2023 -

Caffeine contributes to pain relief

A brief literature review published March 2016 in Anesthesiology and Pain Medicine found that caffeine helps address migraine when used as an adjuvant treatment. The paper's authors noted that caffeine acts on adenosine receptors that are involved in pain sensations, and the substance is present in some over-the-counter (OTC) pain medications. It noted that caffeine possesses potential to address hypnic headache and postdural puncture ...

Improve sleep quality to bolster your resilience against anxiety and depression

August 10, 2023 - adenosine in the brain that accumulates while you are awake and is metabolized while you sleep. The accumulation of sleep drive makes you feel sleepy. (Related: Natural sleep aids: Enjoy a good night of sleep.)

Practice these healthy sleep hygiene habits to help you fall asleep more quickly, remain asleep throughout the night and feel refreshed in the morning.Follow a consistent sleep-wake schedule

Going to bed and waking up at the same time each day can help ...

Feeling tired after enjoying a cup of coffee? You should probably limit your caffeine intake, advise researchers

September 18, 2020 - adenosine from binding to its receptors

Adenosine is a brain chemical that plays a vital role in facilitating sleep; when it binds to its receptors, neural activity slows down and a person feels sleepy. Adenosine levels increase during wake hours and decrease during sleep.

When you drink coffee, caffeine binds to adenosine receptors. But it does not halt the production of adenosine or the body's ability to make more adenosine ...

How to beat caffeine addiction and lessen withdrawal symptoms

October 02, 2018 - adenosine, a chemical that relaxes the nervous system. Since adenosine can't bind, your brain will not feel tired and would continue to produce stimulants for the different brain functions. This leads to an overall feeling of alertness, focus, and motivation.

Unfortunately, regular caffeine intake can alter brain chemistry. The adenosine molecules that have nothing to bind to will signal your brain to make more receptors for it, making it impossible ...

Research finds the performance enhancing benefits of caffeine are more profound in those who don’t drink coffee, tea or energy drinks on a daily basis

February 08, 2018 - adenosine. Adenosine is a substance that can make you feel tired, which builds up during the day and eventually dissipates while you sleep. Essentially, your body thinks caffeine molecules are binding to the parts of the brain where adenosine would normally attach to, causing increased alertness after drinking that cup of coffee," Enright said.

According to the Enright, constant repeated exposure to caffeine causes the adenosine receptors ...

Diets and snoozing: Can the keto diet help you sleep better?

May 14, 2019 - adenosine. Adenosine is important in regulating sleep.

As adenosine builds up in the body throughout the day, it slowly decreases alertness and wakefulness, so during nighttime, the body succumbs to a deeper, slow-wave sleep.

"Studies show that a ketogenic diet promotes adenosine activity in the body, helping to relax the nervous system, as well as reducing inflammation – all of which can help improve sleep,” says Breus.

Another ...

Coffee makes your brain younger: Research shows that by normalizing stress hormones, coffee reverses memory deficits

October 04, 2018 -

Published in the journal Scientific Reports from Nature, a recent study has shown in animals, caffeine actually counteracts age-related cognitive deficits.  Conducted by a cohort of Brazilian researchers from the Instituto de Medicina Molecular (iMM Lisboa), associates from Inserm in Lille, France, and in collaboration with teams from the U.S. and Germany, scientists have shown how a certain receptor in the brain plays a key role in brain aging. Abnormal expression of the adenosine ...

Goka fruit can attenuate insulin resistance symptoms

May 29, 2019 -

In conclusion, supplementation with goka fruit can improve obesity-associated insulin resistance and liver fat accumulation by regulating AMPK activity and lipid metabolism.

Combat obesity with medicinal plants. Learn more at

Journal Reference:

Saito T, Nishida M, Saito M, Tanabe A, Eitsuka T, Yuan SH, Ikekawa N, Nishida H. THE FRUIT OF ACANTHOPANAX SENTICOSUS (RUPR. ET MAXIM.) HARMS IMPROVES INSULIN ...

Nootropics: Not just a fancy way of saying brain vitamins

September 06, 2019 - adenosine receptors. Adenosine is a neuromodulator that binds with specific receptors, slowing down neural activity and inducing sleepiness.


Creatine is an amino acid that your body uses to produce protein and promote muscle growth. It is a popular supplement among athletes.

Creatine is also considered a great fuel for your brain. The amino acid binds with phosphate in your brain to give energy to your brain cells for improved short-term ...

Coffee and tea can keep your heart healthy…but only if you drink in moderation

June 11, 2018 - adenosine. This chemical can be blocked by caffeine, such as the 95 milligrams found in the typical cup of coffee. (Related: Did you know it could do all that? 12 creative uses for coffee.)Moderate levels of caffeine improve heartbeats of post-heart attack patients

Australian researchers discovered this link between caffeine consumption and the stimulant's effects on atrial and ventricular arrhythmia after poring over the results of several population-based studies....

Coffee and coconut oil: The perfect pair?

October 07, 2019 - adenosine, an inhibitory neurotransmitter that acts as a depressant. Once adenosine is blocked, levels of energy-boosting neurotransmitters increase. This leads to people feeling more energized.

2. Protects the liver

The liver performs many important functions in the body, including the breakdown of compounds for energy. Common diseases such as hepatitis and hemochromatosis largely affect the liver, leading to a more severe condition called cirrhosis ...

3 Reasons why Americans suffer from sleep disorders

March 22, 2023 - adenosine.

Adenosine plays many roles, including helping to regulate your sleep-wake cycle, but is not the only molecule that can bind to sleep-promoting receptors in your brain.

To measure how long a substance like caffeine lasts in your body, scientists use a term called "half-life" – the time it takes for the starting amount of the substance to be reduced by half.

According to the Food and Drug Administration, the half-life of caffeine is ...

Why mangosteen should be part of your diet, especially if you’re obese

November 19, 2018 - adenosine monophosphate (AMP)-activated protein kinase and Sirtuin 1.

These findings suggest that mangosteen extract has the ability to help regulate energy metabolism and hepatic lipid homeostasis. The researchers concluded that mangosteen extract has anti-obesity properties due to its effect on energy metabolism and hepatic lipid homeostasis.Mangosteen and its benefits

Mangosteen, also known as the "queen of fruits," is a purple-colored fruit with white ...

A natural way to lose weight with the traditional Korean medicine tongbi-san

May 22, 2019 - adenosine monophosphate-activated protein kinase (AMPK) and decreased the expression of transcription factors in their liver and epididymal fat. These results suggested that tongbi-san can prevent adipogenesis by regulating lipid accumulation and adipogenic-related factors in obese mice.

The researchers concluded that tongbi-san has an inhibitory effect on adipogenesis and may be used as treatment for obesity. Their study was published in the journal BMC Complementary ...

Japanese plum offers protection against fatty liver, reveals study

October 07, 2021 - adenosine monophosphate (AMP)-activated protein kinase (AMPK) activity. When activated in the proper tissues -- like the brain, liver and skeletal muscles -- this brings about multiple benefits, including improved insulin sensitivity, enhanced muscle performance and reduced inflammation, among others.

The results suggest that Japanese plum extract can prevent both alcohol- and free fatty acid-induced oxidative damage and lipid accumulation in liver cells.

Learn ...

Researchers are stunned at the tremendous anticancer potential of turmeric

February 21, 2019 - adenosine triphosphate (ATP)-binding cassette (ABC) transporters, inducing cell apoptosis, inhibiting DNA repair, regulating metabolic reprogramming, or using combination therapy. But even with this information, chemoresistance remains a big challenge to chemotherapy.

There are many natural substances that are being considered as possible solutions to this problem. One of these is turmeric. Previous studies have shown that this superfood can improve the sensitivity ...

Garden thyme essential oil’s antibacterial properties found to be useful in fighting childhood illnesses

July 25, 2018 - adenosine triphosphate].” (Related: Drink a Cup of Thyme Tea Instead of Coffee and Promote Good Health.)

Equally effective at inhibiting bacteria was lemongrass, which the researchers noted greatly enhanced the bactericidal activities of essential oil combinations.

Thus, the researchers that concluded that garden thyme essential oil could be used as a potential drug against S. typhimurium, particularly, against the fever and diarrhea caused by this strain. “Instead ...

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