A government laboratory in Maryland planned to make the circulating monkeypox strain more lethal in a highly controversial research involving mice. It wanted to equip the dominant clade – which mostly causes a rash and flu-like symptoms – with genes from another strain that causes severe disease. (Related: EVIL: Fauci-run NIAID funded animal testing on beagles, Rep. Majorie Taylor Greene reveals.)
The modified virus would have "posed an exceptionally high risk" to the public if it accidentally leaks, according to Dr. Richard Ebright, a microbiologist at Rutgers University in New Jersey.
The scientists in the Maryland lab argue that their work did not involve "enhancing" a pathogen because they were simply swapping natural mutations rather than creating new ones. Meaning, the hybrid could not be more deadly than the existing clades. The plan only received widespread attention in late 2022 amid concerns that the Wuhan coronavirus (COVID-19) may have been borne out of similar experiments using U.S. government grant money in China.
There are two types of monkeypox virus. Clade I causes severe illness and has killed up to 11 percent of infected individuals, while Clade II is more transmissible but less severe. In October 2022, a team of government scientists wanted to insert genes from the more dangerous Clade I into Clade II, making a hybrid strain that could have been both more lethal and more contagious.
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Classified as gain-of-function
Investigators said this would be classified as gain-of-function, which can result in deadlier and more transmissible viruses and is feared to be behind the creation of COVID-19.
While COVID-19 looks more and more like a rebranding of the common cold, the monkeypox creation could have become a full-blown pandemic.
The blueprint to create a mutant monkeypox virus raised major concerns among experts and led to an investigation by the House Energy and Commerce Committee, which recently released the results from its year-and-a-half probe. The report said the Department of Health and Human Services (HHS), NIAID and National Institutes of Health (NIH) repeatedly "obstructed and misled the committee" about whether the risky experiments had been approved and conducted, describing their cooperation with the probe as "unacceptable and potentially criminal."
The investigators wrote: "HHS and the NIH repeatedly told the Committee the experiments had not been 'formally proposed' or 'planned,' had never been approved or conducted, and were not currently under consideration. These repeated assertions were false."
They added that NIAID, a branch of the NIH, should not be trusted to carry out this type of research. "The primary conclusion drawn at this point in the investigation is that NIAID cannot be trusted to oversee its own research of pathogens responsibly. It cannot be trusted to determine whether an experiment on a potential pandemic pathogen or enhanced potential pandemic pathogen poses unacceptable biosafety risk or a serious public health threat."
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