Dr. Pizzorno: Two years ago I became the editor of a new journal called Integrative Medicine, A Clinician's Journal, and what I've done with this journal is create a resource for clinicians, although it can also be read by the educated layperson, and on my board, my editorial board, I have medical doctors, I have naturopathic doctors, I have chiropractors, I have PhDs, I have people from acupuncture, people from nutrition -- basically I'm bringing people from all of the healing arts together to talk about how we can work collaboratively together in the best interests of our patients. So, one of the key elements of our journal is integrated care protocol. So we'll look at a condition like diabetes, for example, and look at when you use, say, the herbs, when you use the nutrients, when you use the drugs, how the drugs and herbs interact with each other, and provide an integrated care profile so that we can provide the best quality care for our patients.
Mike: So, let me ask you about, in the headlines recently, we've seen about other medical journals, this controversy about, now I think 11 of them are saying they're only going to print studies from companies that are willing to print all of the studies. And there's been quite a few accusations of distortions in more conventional journals -- how does your journal differ from that, or does it?
Dr. Pizzorno: Well, I think that's a wonderful trend to see, because I think that indeed there's a lot of negative information and adverse outcomes information on the drugs that has not been properly presented to the clinicians. Our journal doesn't do much original research. We're more interested in integrated protocols, where clinicians have thought through how to do things, and then show how those, how they work, either through controlled studies or through anecdotal reports of patients. So we're not doing basic drug research, and we don't even have, for example, articles on single herbs. I'm not very interested in that -- I'm more interested in integrated care protocols, where we look at everything that can be used.
Mike: So that leads me to I think an important question for readers, which is -- how does a patient assemble a team of integrative care providers?
Dr. Pizzorno: Boy, that's a real challenge, because there are some clinics around where you have practitioners working together, and that's certainly a good start, but most people don't have that ability. So when they go to their doctor, whether it's a medical doctor or a naturopathic doctor, I think their first question would be, "Who do you collaborate with?" If this medical doctor says, "Well, I think this natural medicine stuff is kinda baloney," well, if he were reasonably open-minded he may say, "Well you can use it, it won't hurt you," well, someone like that, why waste your time with them? Go to somebody who says, "Yes, I work well with these people I know that I'm really good in what I do, but I also know there's some areas where I don't have skills, and I have these other people I work with they have high-level skills there, and I'm delighted to work with those people," and that's the kind of doctor you want, regardless of the school of thought. Same thing with a naturopathic doctor -- you go to a naturopathic doctor, and you say, "Well, who do you work with collaboratively?" And they say, "Eh, in that profession they're a bunch of idiots that just kill people." Well, I wouldn't want to go to a naturopathic doctor like that.
Mike: Sadly, it seems though, that so many practitioners in conventional medicine there are still many who are shut, very close minded, to alternative medicine or complementary medicine.
Dr. Pizzorno: I think that's very true, and I think there are unfortunately alternative medicine people whose minds are shut as well. And I thought about this for a lot of years, wondering why we're so hostile towards each other -- I mean, not everybody is, but a lot are, and it occurs to me, we only see each other's failures. So if somebody's happy with what's going on with conventional medicine, they're not going to seek alternatives, and alternatively, someone who is happy with alterative medicine is not going to go seeking conventional medical doctors very often. So it's only when their therapies fail or they get improper diagnosis and treatment that they are likely to go to another practitioner, that other practitioner looks and says, "Well, that wasn't very good care the person got. Boy, these people must not be good health care practitioners." So I think we get a skewed perspective that's not very accurate.
Mike: And then your journal, on the other hand, kind of balances the scale by showing where it works together.
Dr. Pizzorno: Yes, and where it doesn't work together, so we pay just as much attention to drug/herb/nutrient interactions where you have adverse effects. We want to give people good quality, objective, unbiased information about how to practice better medicine, and in many ways, I don't care what you call it, because I think there's a lot of wisdom out there. I think we all have to use the best wisdom available.
Mike: You've led me to another question -- in the press, we always hear about how an herb, usually St. John's Wort, interferes with some prescription drug, but we never hear how a drug interferes with the body or a drug interferes with a nerve.
Dr. Pizzorno: And we should. It's interesting -- many of, maybe the most of side effects from commonly prescribed drugs are due to nutritional abnormalities induced by the drug. And that's one reason why using them both together can be so effective, because if you know what nutritional abnormalities are being induced by the drug, by providing extra amounts of those nutrients, you can help mitigate a lot of the side effects of the drugs.
Mike: Can you give a simple example that people would recognize there?
Dr. Pizzorno: Well, the example I gave already of the coenzyme Q10 being removed by the statin drugs. Another example, and this is very common one, a lot of people are now using cimetadine, and other H2 blockers. Well those H2 blockers, not only do they block the secretion of hydrochloric acid in the stomach, but they also block the secretion of intrinsic factor. Well, intrinsic factor is critical for the absorption of B12. So if somebody's using cimetadine for a long period of time, they're going to develop a B12 deficiency, so we want to give these people extra amounts of B12. Now there are a lot of examples of well-proven nutritional abnormalities induced by drugs that are just being ignored by conventional medicine.
Mike: Because people aren't getting this information from their pharmacists, they're not typically getting it from their doctor, either.
Dr. Pizzorno: Actually, they're more likely to get it from their pharmacist than from their medical doctor, because the pharmacists have better training in the drugs than a medical doctor does.
Mike: Well, that's interesting that you call it a dream -- that's a dream that you are actually helping to make reality, in your books, and with the school. I think a big question people have who are familiar with your work is how do you accomplish so much?
Dr. Pizzorno: Oh! Well, I started out young! I was only 30 years old when I started Bastyr University, so I had a lot of energy then!
Mike: And you have good longevity because you follow your own advice.
Dr. Pizzorno: I do try to follow my own advice. I'm an avid basketball player, and I still play every week with the students, and there's a group of guys I've been playing with for about 15 years, and all but one of the people I started out playing with 15 years ago no longer play anymore. And what was happening, I was noticing that after we played basketball -- and you know, we played for two hours full court, so it was pretty intense -- they'd be popping ibuprofen and aspirin and other anti-inflammatories, and I would be taking glucosamine sulfate and my vitamin C, and my lipoic acid and such.
What was happening was that by taking those anti-inflammatory agents they were decreasing their pain and stiffness afterwards, but they were also blocking the body's ability to repair the damaged tissue, whereas glucosamine sulfate supports the body's own healing process. And so, it's kind of funny, the younger guys are now starting to ask me what I've been taking, because I'm by a sizable margin the oldest person playing with this group of guys.
Mike: And this is glucosamine sulfate, you said, vitamin C, lipoic acid?
Dr. Pizzorno: Right.
Mike: Those are the big three, huh?
Dr. Pizzorno: Well, and other things. I also take more vitamin E, and carnitine. One of the challenges people have is that our mitochondria, which are, you might say, the energy producers in the cells, they wear out over time, and most people, by the time they hit 50, the mitochondria are pretty dysfunctional at that point, and they start going downhill pretty quickly. That's one reason why older people have less energy than young people. Well, it turns out you can delay and slow down the aging process of the mitochondria by using fairly large doses of certain nutrients, and the ones that are of primary importance are lipoic acid, carnitine, vitamin E, and coenzyme Q10. There's actually a fair amount of animal research, and just now we're starting to see human research showing that these are able to substantially improve mitochondrial function in older animals and humans.
Mike: And getting back to COQ10, the production of COQ10 is suppressed by statin drugs, you mentioned.
Dr. Pizzorno: Yes, it is. It's suppressed by stain drugs, and also it's produced in the mitochondria, so as the mitochondria age, it's kind of like a double whammy -- they're being less functional producers of COQ10, which means they're more susceptible to cell damage and they just go down quickly.
You've been reading part four of a five-part interview with Dr. Joseph Pizzorno, the founding president of Bastyr University. Dr. Pizzorno was appointed by President Clinton in December 2000 to the White House Commission on Complementary and Alternative Medicine Policy. President Bush�s administration appointed him to the Medicare Coverage Advisory Committee in February 2003. He is also the co-author of the �Textbook of Natural Medicine� and the �Handbook of Natural Medicine.�