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Science.NaturalNews.com - Conduct powerful scientific research in mere seconds for your book, blog, website article or news report.

https://science.naturalnews.com/related/Bcl-2_protein_down-regulation_and_lymphoma.html

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https://science.naturalnews.com/related/Bcl-2_protein_down-regulation_and_HDL.html

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https://science.naturalnews.com/related/Bcl-2_protein_down-regulation_and_Hematopoietic.html

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https://science.naturalnews.com/related/Bcl-2_protein_down-regulation_and_Hepatoma.html

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https://science.naturalnews.com/related/Bcl-2_protein_down-regulation_and_Irradiation.html

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https://science.naturalnews.com/related/Bcl-2_protein_down-regulation_and_Neuroprotective.html

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Traditional Chinese herbal medicine, insect tea, found to be a potential treatment for cancer

https://naturalnews.com/2018-10-10-insect-tea-found-to-be-a-potential-treatment-for-cancer.html

Bax is a pro-apoptotic protein while Bcl-2 and Bcl-xL are anti-apoptotic proteins. By increasing the levels of Bax in a dose-dependent manner, ITEE neutralizes the anti-apoptotic effects of both Bcl-2 and Bcl-xL and facilitates natural cell death. "...

Beach vitex fruit can induce apoptosis in human colorectal cancer cells

https://naturalnews.com/2019-05-02-beach-vitex-fruit-induces-apoptosis-in-human-colorectal-cancer-cells.html

ATF3 knockdown also decreased V. rotundifolia-mediated cell viability and cell death. - V. rotundifolia downregulated Bcl-2 expression at both protein and mRNA level. ... VITEX ROTUNDIFOLIA FRUIT EXTRACT INDUCES APOPTOSIS THROUGH THE DOWNREGULATION OF ATF3-MEDIATED BCL-2 EXPRESSION IN HUMAN COLORECTAL CANCER CELLS. "...

Cancer breakthrough: Medical nutrient in broccoli found to kill cancer cells

https://naturalnews.com/020444_cancer_prevention.html

"A cancer cell with a lot of Bcl-2 has increased resistance to chemotherapy drugs that are used to destroy the tumor," says lead researcher Dr. ... "We've found that Bcl-2 can't protect cancer cells against certain isothiocyanates." "...

Beach vitex herb found to possess anticancer properties, according to study

https://naturalnews.com/2019-05-16-beach-vitex-has-anticancer-properties.html

V. rotundifolia downregulated Bcl-2 expression at both protein and mRNA level. ATF3 knockdown by ATF3 siRNA blocked V. rotundifolia-mediated downregulation of Bcl-2. Bcl-2 or B-cell lymphoma 2 is a regulator protein involved in apoptosis. Based on these findings, the researchers concluded that V. rotundifolia induces apoptosis in human colorectal cancer cells by activating ATF3 expression through transcriptional regulation and subsequently ...

Lagopsis supine ethanol extract can inhibit colorectal cancer cell proliferation and reduce tumor growth

https://naturalnews.com/2020-06-12-lagopsis-supine-inhibits-colorectal-cancer-tumor-growth.html

The researchers also determined the protein expression levels of pSTAT3, pJAK2, STAT3, JAK2, Bcl-2 and caspase 3, as well as the mRNA levels of genes downstream of STAT3. ... Ls also decreased the expression of pSTAT3, pJAK2 and Bcl-2 in a dose-dependent manner. "...

Investigating the anti-tumor effect of elemene on pancreatic cancer cell lines

https://naturalnews.com/2020-02-18-anti-tumor-effect-elemene-pancreatic-cancer.html

. - They used immunoblotting and immunohistochemical methods to detect the expression of P53 and Bcl-2 in the transplanted tumors. - H and E staining allowed them to detect histopathological changes in each group. - Elemene inhibited the proliferation of BxPC-3 and Panc-1 cells in vitro in a dose-dependent manner. - It also induced cell cycle arrest in the S phase after 12 hours of treatment. - In vivo, elemene significantly reduced tumor size in the high dosage group without causing ...

Moxibustion is an effective alternative cancer treatment, according to study

https://naturalnews.com/2019-02-05-moxibustion-is-an-effective-alternative-cancer-treatment.html

Moreover, it also inhibited B-cell lymphoma 2 (bcl-2), tumor protein P53, and cellular Myc (C-MYC), which are all associated with cell death and the production of cancer cells. ... Their leaves contain powerful compounds that protect you from diabetes Next : Architect shares his experience of how magnet therapy cured his OCD - More news on bcl-2 Moxibustion is an effective alternative cancer treatment, according to study - Disqus Take Action: Support Natural ...

Chinese herbal formula wu mei wan reduces insulin resistance, protects pancreas, prevents diabetes

https://naturalnews.com/2019-07-18-chinese-herbal-formula-reduces-insulin-resistance-protects-pancreas-prevents-diabetes.html

WMW also protected the pancreatic beta cells from apoptosis by decreasing caspase-12 expression and increasing Bcl-2 expression. Bcl-2 is an anti-apoptotic protein. Additionally, WMW reversed the upregulation of IL-1B, IL-18, MCP-1a, and macrophage-specific surface glycoprotein F4/80 in diabetic mice. "...

TCM medicines confirmed to accelerate cell death of breast cancer tumors

https://naturalnews.com/2018-03-17-tcm-medicines-accelerate-cell-death-breast-cancer-tumors.html

However, Bid and Bax are pro-apoptotic genes, whereas Bcl-2 and survivin are anti-apoptotic genes. The expression of Bid and Bax genes was enhanced, and Bcl-2 and survivin were suppressed. "...

TCM's Yanghe Huayan found to have potent anti-tumor effects against breast cancer

https://naturalnews.com/2019-10-14-yanghe-huayan-has-potent-anti-tumor-effects.html

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Unlock white sesame flour's antioxidant and brain-protecting effects

https://naturalnews.com/2019-08-14-white-sesame-flour-has-antioxidant-and-brain-protecting-effects.html

The researchers also reported that WS-wsf enhanced Bcl-2 protein expression and Akt phosphorylation. ... Bcl-2 is an outer mitochondrial membrane protein that inhibits the apoptosis . These results further prove that WS-wsf has anti-apoptotic activity. "...

Chinese medicine formula Wu-Mei-wan found to prevent Type 2 diabetes

https://naturalnews.com/2019-06-13-chinese-medicine-formula-wu-mei-wan-prevents-type-2-diabetes.html

mg/kg bw. - They collected blood samples from the mice to determine fasting blood glucose (FBG) and serum insulin levels. - They measured the expression of proteins related to apoptosis, such as cysteinyl aspartate-specific proteinase 12 (caspase-12) and B-cell leukemia 2 (Bcl-2), using Western blot. - They used enzyme-linked immunosorbent assay (ELISA) to test for the presence of interleukin-1 beta (IL-1B), interleukin-18 (IL-18), monocyte chemoattractant protein-1 alpha ...

Sophoraflavanone G found to induce cell death of human leukemia cells

https://naturalnews.com/2019-07-13-sophoraflavanone-g-induces-cell-death-in-leukemia-cells.html

. - In addition, SG activated caspase-3 and -9; it also downregulated Bcl-2 and Bcl-xL. - SG upregulated Bax, as well as released cytochrome c from the mitochondria into the cytoplasm. ... The American Journal of Chinese Medicine. 2 February 2016;44(01):165–176. DOI: 10.1142/S0192415X16500117 Previous :Certain compounds in milk can protect against hypertension – study Next : Can we find a cleaner way to extract hydrogen from water? "...

Chinese skullcap can prevent liver injury caused by heart failure

https://naturalnews.com/2019-08-19-chinese-skullcap-prevents-liver-injury-caused-by-heart-failure.html

In addition, baicalein treatment increased B-cell lymphoma 2 (Bcl-2) and reduced Bax levels in the liver. Both Bcl-2 and Bax are proteins that regulate cell death. Baicalein also increased the phosphorylation of prosurvival kinases, including Akt and extracellular signal-regulated kinases 1 and 2 (ERK1/2). "...