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Traditional Chinese herbal medicine, insect tea, found to be a potential treatment for cancer


Bax is a pro-apoptotic protein while Bcl-2 and Bcl-xL are anti-apoptotic proteins. By increasing the levels of Bax in a dose-dependent manner, ITEE neutralizes the anti-apoptotic effects of both Bcl-2 and Bcl-xL and facilitates natural cell death. "...

Beach vitex fruit can induce apoptosis in human colorectal cancer cells


ATF3 knockdown also decreased V. rotundifolia-mediated cell viability and cell death. - V. rotundifolia downregulated Bcl-2 expression at both protein and mRNA level. ... VITEX ROTUNDIFOLIA FRUIT EXTRACT INDUCES APOPTOSIS THROUGH THE DOWNREGULATION OF ATF3-MEDIATED BCL-2 EXPRESSION IN HUMAN COLORECTAL CANCER CELLS. "...

Beach vitex herb found to possess anticancer properties, according to study


V. rotundifolia downregulated Bcl-2 expression at both protein and mRNA level. ATF3 knockdown by ATF3 siRNA blocked V. rotundifolia-mediated downregulation of Bcl-2. Bcl-2 or B-cell lymphoma 2 is a regulator protein involved in apoptosis. Based on these findings, the researchers concluded that V. rotundifolia induces apoptosis in human colorectal cancer cells by activating ATF3 expression through transcriptional regulation and subsequently ...

Cancer breakthrough: Medical nutrient in broccoli found to kill cancer cells


"A cancer cell with a lot of Bcl-2 has increased resistance to chemotherapy drugs that are used to destroy the tumor," says lead researcher Dr. ... "We've found that Bcl-2 can't protect cancer cells against certain isothiocyanates." "...

Moxibustion is an effective alternative cancer treatment, according to study


Moxibustion is an effective alternative cancer treatment, according to study Tuesday, February 05, 2019 by: Ralph Flores bcl-2 , C-MYC , gastric cancer , gastric mucosa dysplasia , Gastric precancerous lesions , moxibustion , P53 Bypass censorship by sharing this link: https://www.distributednews.com/200562.html Copy URL - (Natural News ) When people think of traditional Chinese medicine (TCM), one of the things that come to mind is acupuncture and herbs. ... Moreover, it also ...

Lagopsis supine ethanol extract can inhibit colorectal cancer cell proliferation and reduce tumor growth


The researchers also determined the protein expression levels of pSTAT3, pJAK2, STAT3, JAK2, Bcl-2 and caspase 3, as well as the mRNA levels of genes downstream of STAT3. ... Ls also decreased the expression of pSTAT3, pJAK2 and Bcl-2 in a dose-dependent manner. "...

Investigating the anti-tumor effect of elemene on pancreatic cancer cell lines


. - They used immunoblotting and immunohistochemical methods to detect the expression of P53 and Bcl-2 in the transplanted tumors. - H and E staining allowed them to detect histopathological changes in each group. - Elemene inhibited the proliferation of BxPC-3 and Panc-1 cells in vitro in a dose-dependent manner. - It also induced cell cycle arrest in the S phase after 12 hours of treatment. - In vivo, elemene significantly reduced tumor size in the high dosage group without causing ...

Chinese herbal formula wu mei wan reduces insulin resistance, protects pancreas, prevents diabetes


WMW also protected the pancreatic beta cells from apoptosis by decreasing caspase-12 expression and increasing Bcl-2 expression. Bcl-2 is an anti-apoptotic protein. Additionally, WMW reversed the upregulation of IL-1B, IL-18, MCP-1a, and macrophage-specific surface glycoprotein F4/80 in diabetic mice. "...

TCM medicines confirmed to accelerate cell death of breast cancer tumors


However, Bid and Bax are pro-apoptotic genes, whereas Bcl-2 and survivin are anti-apoptotic genes. The expression of Bid and Bax genes was enhanced, and Bcl-2 and survivin were suppressed. "...

Unlock white sesame flour's antioxidant and brain-protecting effects


The researchers also reported that WS-wsf enhanced Bcl-2 protein expression and Akt phosphorylation. ... Bcl-2 is an outer mitochondrial membrane protein that inhibits the apoptosis . These results further prove that WS-wsf has anti-apoptotic activity. "...

Sophoraflavanone G found to induce cell death of human leukemia cells


. - In addition, SG activated caspase-3 and -9; it also downregulated Bcl-2 and Bcl-xL. - SG upregulated Bax, as well as released cytochrome c from the mitochondria into the cytoplasm. ... The American Journal of Chinese Medicine. 2 February 2016;44(01):165–176. DOI: 10.1142/S0192415X16500117 Previous :Certain compounds in milk can protect against hypertension – study Next : Can we find a cleaner way to extract hydrogen from water? "...

TCM's Yanghe Huayan found to have potent anti-tumor effects against breast cancer


TCM’s Yanghe Huayan found to have potent anti-tumor effects against breast cancer Monday, October 14, 2019 by: Evangelyn Rodriguez alternative medicine , angiogenesis , anti-tumor , anticancer , apoptosis , Bax protein , Bcl-2 protein , breast cancer , breast cancer mortality , cancer cures , cancer prevention , cancer solutions , cancer treatment , chemopreventive , disease treatments , goodcancer , goodhealth , goodmedicine , goodscience , herbal medicine , Herbs , malignant ...

Chinese medicine formula Wu-Mei-wan found to prevent Type 2 diabetes


mg/kg bw. - They collected blood samples from the mice to determine fasting blood glucose (FBG) and serum insulin levels. - They measured the expression of proteins related to apoptosis, such as cysteinyl aspartate-specific proteinase 12 (caspase-12) and B-cell leukemia 2 (Bcl-2), using Western blot. - They used enzyme-linked immunosorbent assay (ELISA) to test for the presence of interleukin-1 beta (IL-1B), interleukin-18 (IL-18), monocyte chemoattractant protein-1 alpha ...

Healing plants: Silymarin from milk thistle found to have anti-cancer properties


Using western blot analysis, the researchers found that silymarin increased the expression of the apoptotic activator Bax, activated the tumor suppressors JNK and p38, and decreased the levels of the antiapoptotic proteins ERK1/2 and Bcl?2 in a dose?dependent manner. By inhibiting the phosphorylation of ERK and Bcl-2 and activating p38, JNK and Bax in human gastric cancer cells, silymarin was able to induce cancer cell death and prevent tumor growth. "...

Chinese skullcap can prevent liver injury caused by heart failure


In addition, baicalein treatment increased B-cell lymphoma 2 (Bcl-2) and reduced Bax levels in the liver. Both Bcl-2 and Bax are proteins that regulate cell death. Baicalein also increased the phosphorylation of prosurvival kinases, including Akt and extracellular signal-regulated kinases 1 and 2 (ERK1/2). "...

Can this summer lawn weed help protect you from cervical cancer? Researchers say YES


The researchers also found that POL-P3b protects against tumor-induced apoptosis by activating the TLR4/PI3K/AKT-NF-kB signaling pathway, which increased the expression of Bcl-2. Bcl-2 is a regulator of cell death and is known to inhibit apoptosis by inactivating pro-apoptotic proteins . "...

Allyl isothiocyanate, a compound present in human diets, found to induce cell toxicity in breast cancer cell lines


. - In this study, the researchers found that AITC stimulated reactive oxygen species and Ca2+ production, as well as reduced the mitochondrial membrane potential. - It also increased the activity of caspase-8, -9 and -3 in both cell lines; caspases play essential roles in programmed cell death and inflammation. - In addition, AITC induced mitochondrial-mediated apoptosis. - There was a significant decrease in the levels of the anti-apoptotic protein Bcl-2 together with ...

Prevent cancer with chlorogenic acid-rich foods and supplements


. - The researchers cultured human cervical (HeLa), liver (HepG2), breast (MCF7), colon cancer (HCT-15, HCT-116), cell lines and mouse B16-F1, EAC, normal cell line MEF (STO). - The researchers found that CGA7 treatment induces dose- and time-dependent apoptosis or cell death in different cancer cell lines. - The CGA7-induced apoptosis was characterized by DNA fragmentation, PARP-1 cleavage, caspase-9 activation, and downregulation of Bcl-2 — an anti-apoptotic protein — ...

A look into the anti-carcinogenic effects of Portulaca oleracea polysaccharides


. - It also protected intestinal DC against tumor-induced apoptosis by activating the TLR4/PI3K/AKT-NF-kB signaling pathway, which increased Bcl-2 and mitochondrial calcium levels, prevented the release of cytochome c from mitochondria and reduced the expression of caspase 3. ... DOI: 10.1186/s12906-019-2582-9 Previous :Under-investigated plants from the myrtle family found to have antibacterial activity Next : Exploring the vasolidatory benefits of Rosmarinic acid - More news on ...

Chinese skullcap shown to improve lung injuries caused by myocardial ischemia


. - It also improved Bcl-2 and decreased p53, Bax, and cytochrome c levels in the lungs. ... - More news on alternative medicine Nutritional science: Lower your risks of heart attack and death from cancer by taking vitamin D and fish oil supplements Researchers investigate green tea compounds that may help resolve antibiotic resistance Food scientists recommend daily consumption of whole eggs to reduce your risk of heart disease and stroke The healing protein: Addressing thyroid ...