How the researchers carried out the study For the study, the researchers looked at the influence of growth hormone signaling on AgRP neurons in mice with AgRP-specific growth hormone receptor ablation or AgRP GHR knockout (AgRP GHR KO) mice and a control group comprising wild-type mice. ... In AgRP GHR KO mice, their energy expenditure decreased significantly less. This suggested that they failed to save energy as efficiently as the control mice. "...
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