Wednesday, May 04, 2016 by: Daniel Barker
Tags: prostate cancer drugs, Alzheimer''s disease, side effects
Patients with prostate cancer who received hormone therapy were 23 percent more likely to develop depression and 29 percent more likely to have inpatient psychiatric treatment than men who received alternative treatments, the study found. ...
From six months to three years after diagnosis, 7.1 percent of the men on hormone therapy had new cases of depression, compared with 5.2 percent of the others in the study.
During this period, 2.8 percent of men on hormone therapy had inpatient psychiatric treatment, compared with 1.9 percent of their peers. In addition, 3.4 percent received outpatient psychiatric services, versus 2.5 percent of the other men.
The take-home message is that the list of potential side effects of hormone therapy is continuing to grow. ...
Any man with prostate cancer considering hormone therapy should find out from their doctor exactly how big the benefit is expected to be in their specific situation so they can weigh it against the list of possible side effects.
Patients in the study who had been treated with ADT had about a 1.88 times increased rate of being diagnosed with Alzheimer's disease in a median follow-up period of 2.7 years compared with prostate cancer patients who did not receive ADT, the study found. The subset of men treated with ADT for longer than 12 months had a 2.12 higher risk — more than double that of prostate cancer patients not treated with ADT.
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